Study of PEDRI (Proton Electron Double Resonance Imaging)

PEDRI（质子电子双共振成像）研究

• 批准号: 11450157
• 负责人: ONO Mitsuhiro
• 金额: $ 8.19万
• 依托单位: Yamagata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-11450157/
• 关键词: Double resonance; microwave applicator; cut waveguide; waveguide with flange; TE_<101> cavity resonator; conducting plate; magnetic field; homogeneity; エレクトロン; 同時共鳴; イメージング; PEDRI; NMR; EPR; ESR; 二重共鳴; インビボ; マイクロ波; ラジオ波

In order to develop a 0.2 Testar PEDRI (Proton Electron Double Resonance Imaging), microwave applicators have been studied.The frequencies are 8 MHz for NMR and 5.6 GHz for EPR.A NMR RF applicator is a solenoid or a birdcage coil. An EPR microwave applicator must be able to withstand 5 W CW and to generate homogeneous magnetic fields of about 10 mm X 20 mm. In this study, a basic applicator consists of a TE_<10> rectangular waveguide to obtain microwave magnetic fields mentioned above. We measured distribution of magnetic fields of (1) a waveguide without a flange, (2) a waveguide with a flange, (3) a TE101 cavity resonator terminated by grids and (4) a conducting plate. The inner diameter of the pick up coil used for the measurement of the magnetic field is 1 mm. The diameter of the wire is 0.3 mm.Following three matters have become obvious. (1) The magnetic field strength at the aperture of a cut waveguide is about 1/10 of the maximum value, the magnetic field mainly concentrates at the center of the longer side of the waveguide-wall and the distribution of the field is not homogeneous. The magnetic field distribution homogeneity which is defined as the minimum value /the maximum value of the field strength is 0.09 at the aperture and is 0.45 at the outer side of the aperture. (2) The magnetic field distribution homogeneity of the waveguide with the flange is 0.14 at the aperture and is better homogeneous than the magnetic field distribution at the aperture, that is, 0.70 at the outer side of the aperture. (3) The best value of the field distribution homogeneity for the TE101 cavity resonator terminated by grids is 0.37. (4) The homogeneity of the field strength distribution for a conducting plate which is terminated by the open-circuit and connected to the cut waveguide has the best homogeneity.

为了开发 0.2 Testar PEDRI（质子电子双共振成像），对微波施加器进行了研究。NMR 的频率为 8 MHz，EPR 的频率为 5.6 GHz。NMR RF 施加器是螺线管或鸟笼线圈。 EPR 微波辐射器必须能够承受 5 W CW 并产生约 10 mm X 20 mm 的均匀磁场。在本研究中，基本施加器由TE_<10>矩形波导组成，以获得上述微波磁场。我们测量了 (1) 不带法兰的波导、(2) 带法兰的波导、(3) 由网格终止的 TE101 空腔谐振器和 (4) 导电板的磁场分布。用于测量磁场的拾波线圈的内径为1毫米。线材的直径为0.3mm。以下三点变得显而易见。 (1) 切割波导孔径处的磁场强度约为最大值的1/10，磁场主要集中在波导壁长边的中心，场分布不均匀。定义为场强的最小值/最大值的磁场分布均匀度在孔径处为0.09，在孔径外侧为0.45。 (2)带凸缘的波导在孔径处的磁场分布均匀度为0.14，比孔径处的磁场分布均匀性好，即孔径外侧的0.70。 (3) 网格端接TE101空腔谐振器的场分布均匀性最佳值为0.37。 (4) 终止于开路并连接到切割波导的导电板的场强分布均匀性最好。

项目成果

Akihiko Suenaga,Mitsuhiro Ono,Hiroshi Hirata,and Hitoshi Susaki: "On optimum bridge angle of a 300MHz bridged loop-gap resonator"International Symposium on In vivo ESR Spectroscopy, In conjunction with 5^<th> Conference on In vivo ESR, held in Kyushu Univ

Akihiko Suenaga、Mitsuhiro Ono、Hiroshi Hirata 和 Hitoshi Susaki：“关于 300MHz 桥接环隙谐振器的最佳桥角”国际体内 ESR 光谱研讨会，与第 5 届体内 ESR 会议同时举行

Mitsuhiro Ono and Hiroshi Hirata: "A design of 300MHz bridged loop-gap resonators used for in vivo EPR imaging"International Symposium on In vivo ESR Spectroscopy, In conjunction with 5^<th> Conference on In vivo ESR, held in Kyushu University, Fukuoka, J

Mitsuhiro Ono 和 Hiroshi Hirata：“用于体内 EPR 成像的 300MHz 桥接环隙谐振器的设计”国际体内 ESR 光谱研讨会，与第五届体内 ESR 会议联合在九州大学举行，

Mitsuhiro Ono, et al.: "Development of 350MHz pulsed EPR"International workshop on Techniques and Bio-Medical Applications of In Vivo EPR and PEDRI. 42-42 (1999)

Mitsuhiro Ono 等人：“350MHz 脉冲 EPR 的开发”体内 EPR 和 PEDRI 技术和生物医学应用国际研讨会。

M.Ono, A.Suenaga, H.Hirata: "Experimental Investigation of RF Magnetic Field Homogeneity in a Bridged Loop-Gap Resonator"Magnetic Resonance in Medecine. 47. 415-419 (2002)

M.Ono、A.Suenaga、H.Hirata：“桥接环隙谐振器中射频磁场均匀性的实验研究”医学中的磁共振。

Mitsuhiro Ono, Akihiko Suenaga, Hiroshi Hirata: "Experimental Investigation of RF Magnetic Field Homogeneity in a Bridged Loop-Gap Resonator"Magnetic Resonance in Medicine. 47. 415-419 (2002)

Mitsuhiro Ono、Akihiko Suenaga、Hiroshi Hirata：“桥接环隙谐振器中射频磁场均匀性的实验研究”医学中的磁共振。