Mutual Separation of Metal Chelate by Solvent Extraction-Micellar Electrokinetic Capillary Chromatography

溶剂萃取-胶束电动毛细管色谱法相互分离金属螯合物

基本信息

批准号：
04453034
负责人：
KAWAMOTO Hiroshi
金额：
$ 4.16万
依托单位：
Gunma University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1992
资助国家：
日本
起止时间：
1992 至 1994
项目状态：
已结题

项目摘要

1.Mutual Separation of Metal Ions by Dithizone Extraction-Isotachophoresis on the Basis of HSAB PrincipleBased on the hard and soft acids and bases (HSAB) principle, a method for extraction of metal ions with dithizone was developed for preconcentration and separation of trace metal ions. The extracted metal ions in organic phase were back-extracted to EDTA solution. The resulting solution was applied to isotachophoretic analysis. The separation of zinc (II), cadmium (II) and lead (II) at 10-6 mol dm03 level could performed by the present method.2.Mutual Separation Method for Metal Ions by Solvent Extraction with Diethyldithiocarbamic Acid and Isotachophoresis on the Basis of HSAB Principle.On the basis of the HSAB principle, a method for extraction of metal ions with diethyldithiocarbamic acid (DDTC) consisting of the preconcentration and separation of trace metal ions was developed. Metal ions extracted into CCl_4 were back-extracted into Cu-EDTA solution which was applied to isotachophoretic analysis. This method made possible the separation of Cd^<II>, Fe^<II>, Pb^<II> and Zn^<II> at 10^<-6> mol dm^<-3> level.Back-Extraction Mechansim of Dithizonato Chelate.The back-extraction mechanism of dithizonato Chelate (MR_2, M=Zn, Cd) was studied. And it was found that the rate-determining step is the reaction of MR_2^*+H^**MR^*+HR in the aqueous phase following the rapid partition of MR_2 between the organic and aqueous phase and formation of ring-opened complex (MR_2^*) at the initial stage of shaking.

1.基于基于HSAB原理在硬质和软酸和碱基（HSAB）原理上，通过二硫酮提取 - 异位液（HSAB）原理对金属离子的敏感分离，开发了一种用于提取二硫酮金属离子的方法。将有机相的提取的金属离子反射为EDTA溶液。将最终的溶液应用于等渗疗法分析。在10-6 mol DM03水平上可以通过本方法进行锌（II），镉（II）和铅（ii）的分离。2。金属离子的液体分离方法通过用二硫代二硫代氨基酸和异位含量的溶剂萃取基于金属离子。在HSAB原理的基础上，开发了由丁二醇果酸（DDTC）提取金属离子的一种方法，该方法由痕量金属离子的预浓缩和分离组成。将提取到CCL_4的金属离子反射到Cu-EDTA溶液中，该溶液应用于同骨疗法分析。这种方法使Cd^<ii>，Fe^<ii>的分离有可能，Pb^<ii>和Zn^<ii> at 10^<-6> mol dm^<-3> lack.back-back-rettraction mechansim研究了二硫代酮螯合。发现速率确定的步骤是MR_2+h^** MR^*+HR在MR_2在有机相和水相之间快速分配后的水相中的反应，并形成了环的复合物。（MR_2^*）在摇晃的初期。