Study on the relationship between morphological and functional changes in eight nerve lesion.

八种神经病变形态与功能变化关系的研究

• 批准号: 03454404
• 负责人: KOMATSUZAKI Atsushi
• 金额: $ 4.22万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1991
• 资助国家: 日本
• 起止时间: 1991 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-03454404/
• 关键词: eight nerve; acoustic neurinoma; vestibular endorgan; internal auditory canal; calcium carbonate; 骨硬化度; 炭酸カルシウム; 聴神経腫瘍起源神経; 聴力保存; 内耳道骨硬度; 前庭感覚細胞; 超微細形態; 前庭感覚上皮; 骨量ファントム; 温度眼振; 前庭器官; 誘発電位

Eight nerve lesions in the internal auditory meatus especially in cases of acoustic tumor were studied.The results obtained were as follows.1. Morphological changes were studied using electronmicroscope and no special pathological changes were obtained on the vestibular endorgan epithelia even though there were marked functional changes by caloric stimulations.2. There were no special relationship between the pathology of the vestibular endorgan and the nerve of origin of tumor.3. In order to investigate that the internal auditory canal is enlarged usually at the porus part than the lateral part in cases of acoustic tumor, content of calcium carbonate was measured by quantitative CT for determination of bone mineral density.The highest mean value was found in the fundus posterior whereas the lowest in the porus anterior, and there was a significant difference between the value of the fundus and porus.These results suggest that one of the factors to enlarge on the internal auditory canal especially at the porus.

内部听觉肉类中的八个神经病变，尤其是在声学肿瘤的情况下。获得的结果如下。1。使用电子显微镜研究了形态学的变化，即使卡路里刺激有明显的功能变化，也没有在前庭内形上皮上获得特殊的病理变化。2。前庭内岩的病理与肿瘤起源神经之间没有特殊的关系。3。为了调查内部听觉管通常在孔的一部分扩大，而不是在声学肿瘤的情况下的横向部分，碳酸钙的含量是通过定量CT来测量的，以确定骨矿物质密度的确定最高的平均值。在底部的后部发现了最低的孔子，而在孔中的一部分是最低的，而在孔中的效果最低，而孔的价值则是重要的差异。在内部听觉运河上，尤其是在孔道上。

项目成果

小松崎 篤: "疾患の病態・治療「聴神経腫瘍」" 日本耳鼻咽喉科学会会報. 96. 1986-1989 (1993)

Atsushi Komatsuzaki：“‘听神经瘤’疾病的病理学和治疗”日本耳鼻喉科学会通报 96。1986-1989 (1993)

Watanabe K,Komatsuzaki A: "Membranous cytoplasmic bodies in the lateral wall of the cat cochlea." Ann Otol Rhinol Laryngol. 101(4). 355-359 (1992)

Watanabe K，Komatsuzaki A：“猫耳蜗侧壁的膜细胞质体。”

奥野 秀次: "骨導蝸電図での聴神経複合活動電位の同側および対側刺激による差異" Audiology Japan. 35. 690-694 (1992)

Hidetsugu Okuno：“骨传导耳蜗描记术中同侧和对侧刺激引起的听神经复合体动作电位的差异”日本听力学 35. 690-694 (1992)。

K.Ichimura: "Oncogene Expression in Acoustic Neurinomos." Biological Aspects of Brain Tumors.337-342 (1991)

K.Ichimura：“声学神经元中的癌基因表达。”

小松崎 篤: "目で見る耳鼻咽喉科臨床検査ー注視眼振および頭位眼振の検査ー" JOHNS. 7. 1493-1498 (1991)

Atsushi Komatsuzaki：“视觉耳鼻喉科临床检查 - 凝视眼球震颤和位置性眼球震颤的检查”JOHNS。7. 1493-1498 (1991)