Studies on a blood pump based on a novel principle (eccentric revolution)

基于新原理（偏心旋转）的血泵研究

• 批准号: 01490024
• 负责人: FUKUI Yasuhiro
• 金额: $ 3.84万
• 依托单位: Tokyo Denki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1991
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-01490024/
• 关键词: blood pump; centrifugal pump; seal-less pump; artificial organ; シ-ルレスポンプ; 揺動回転; 溶血試験; 負荷特性; スクロ-ル運動

A new blood pump was developed in this study. It has only elastic membrane inside the pump case. Between the pump case and elastic membrane, fluid or air which, has different specific gravity than blood is contained. By rotating the pump case eccentrically while prohibiting revolution of pump case itself, flow and pressure were obtained from the pump. The pump has very simple structure and does not have any impeller, vanes, or valves, which bring about various problems such as thrombus formation and leakage through seals, which limit prolonged usage of the pump. This pumping principle is promising for blood pump capable of longer term application. The pump has the following characteristics :1)The generated pressure and flow are proportional to the square of the revolution of the pump case.2)Pump output is proportional to the eccentricity of the pump case revolution.3)In the present experimental system, flow rate of 700 mL/min against 650 mmH_2O was obtained at 650 rpm of revolution.4)There is an optimal amount of air or fluid contained in the space between the elastic membrane and pump case. The pump output was maximum when the elastic membrane alightly closed the inlet port. It suggested that the elastic membrane functioned as a kind of a valve in this pump.5)Flow from the pump was not continuous flot4, but pulsatile flow synchronizing the pump case revolution.6)The pump was considered to have both characteristics of centrifugal pump and positive displacement pump.

本研究开发了一种新型血泵。它的泵壳内只有弹性膜。在泵壳和弹性膜之间盛有比重与血液不同的液体或空气。通过使泵壳偏心旋转，同时禁止泵壳本身公转，从泵获得流量和压力。该泵结构非常简单，没有任何叶轮、叶片或阀门，这会带来血栓形成、密封件泄漏等各种问题，限制了泵的长期使用。这种泵送原理对于能够长期应用的血泵来说是有希望的。该泵具有以下特点：1）产生的压力和流量与泵壳转数的平方成正比。2）泵的输出与泵壳转数的偏心率成正比。3）在本实验系统中，在650 rpm转速下获得700 mL/min对650 mmH_2O的流量。4)弹性膜和泵壳之间的空间中存在最佳的空气或液体量。当弹性膜轻微关闭入口时，泵的输出最大。这表明弹性膜在该泵中起到了一种阀门的作用。5）泵的流量不是连续流动，而是与泵壳旋转同步的脉动流。6）该泵被认为具有离心泵的两种特性和正排量泵。

项目成果

増澤 徹: "医療用インテリジェント制御システムの開発ー血圧制御への応用ー" 医用電子と生体工学. 28. 308 (1990)

Toru Masuzawa：“医疗用智能控制系统的开发 - 在血压控制中的应用 -”医疗电子和生物工程 28. 308 (1990)。

Sakuma I., Miyashita O., Fukui Y. and Mizusawa K.: "Development of a Blood Pump by Vessel Revolution" Japanese J. of Medical and Biological Engineering. 27, suppl.405 (1989)

Sakuma I.、Miyashita O.、Fukui Y. 和 Mizusawa K.：“通过容器革命开发血泵”日本医学和生物工程杂志。

A.Funakubo: "Development of a Compct Extracorporeal Membrane Oxygenation (ECMO) System" Artificlal Organs. 15-1. 56-65 (1991)

A.Funakubo：“紧凑型体外膜氧合（ECMO）系统的开发”人工器官。

A.Funakubo: "Development of a Compact Extracorporeal Membrance Oxygention (ECMO)System" Artificial Organs. 15-1. 56-65 (1991)

A.Funakubo：“紧凑型体外膜氧合（ECMO）系统的开发”人工器官。

増澤 徹: "医療用インラリジェント制御システムの開発ー血圧制御への応用ー" 医用電子と生体工学. 28. 308- (1990)

Toru Masuzawa：“医疗间接控制系统的开发 - 在血压控制中的应用”医疗电子和生物工程 28. 308- (1990)。