Developmenth of the ultrasound device for thr preoperative lacalization of parathyroid tumor

甲状旁腺肿瘤术前定位超声装置的研制

基本信息

批准号：
60870057
负责人：
TAJIMA Atsushi
金额：
$ 3.2万
依托单位：
Hamamatsu University School of Medicine
依托单位国家：
日本
项目类别：
Grant-in-Aid for Developmental Scientific Research
财政年份：
1985
资助国家：
日本
起止时间：
1985 至 1987
项目状态：
已结题

项目摘要

We developed 3 types of mechanical sector scamer to predict the localization of parathyorid tumor:type I, II and III. Both of type and II are 7.5 MHz scanners;typeIII 10 MHz scanner. Type I had a 2 cn focal distance with water bag at the scanhead. The typeII consisted of a 3 cm focal distance and polyethylen protruding scanhead. On the other hand, the focal distance of typeIII (10 MHz) with water bag scanheas was 1 cm.All scanners were equiped with the ultrasonic real-time guidance system(Aloka SSD-125^r). Ultrasonographic investigations were performed in 6 cases of primary hyperparathyroidism (PHP) and 4 parients with secondary hyperparathyroidism (SHP). In these saces, computed tomography (CT) and scintigraphy(^<201> TL) were carried out,too.Among 3 types of scanner,typeII was mainly used,since this type gave the most clear picture and typell was operated easily. TypeII was namely the bast.Compared with conventinal electronic real-time linear scanner of 5 MHz,typell depicted more clearly abnormal parathyroid glands and could detect smaller senoma or hyperplasia.The predictability by ultrasonography (US),CT and RI was evaluated compared with operative findings,respctively. The preoperative localization of 6 parathyoid adenomas and 14 hypertrophied parathyroid glands were examined. In 4 parathyroid gland under 0.5g of weighr, the diagnostic accuracy of US was 75%, while that of CT was 50% and no gland was detected by RI. In 6 parathyroid gland from 0.5g to 1.0g the predictability was 50% by US,17%by CT and 33% by RI.As to 10 parathroid gland over 1.0g, the diagnotsic accuracy of US,CT,and RI was 90%,70%and 70%, respectively. US had the higher overall sensitivity than CT and RI. The minimum weight of the detectable parathyroid gland was 150mg,150mg and 500mg by US,CT and RI,respctively.Ultrasonography during the operation did not give the picture of parathyroid gland clearly. Similarly,the percutaneoud parathyroid diopsy guided by US was not successful.

我们开发了 3 种类型的机械扇形骗局来预测甲状旁腺肿瘤的位置：I 型、II 型和 III 型。类型和II均为7.5 MHz扫描仪；类型III为10 MHz扫描仪。 I 型焦距为 2 cn，扫描头上有水袋。 II 型由 3 cm 焦距和聚乙烯突出扫描头组成。另一方面，带有水袋扫描仪的III型（10 MHz）焦距为1 cm。所有扫描仪均配备超声波实时引导系统（Aloka SSD-125^r）。对 6 例原发性甲状旁腺功能亢进症 (PHP) 和 4 例继发性甲状旁腺功能亢进症 (SHP) 患者进行了超声检查。在这些情况下，还进行了计算机断层扫描（CT）和闪烁扫描（^<201>TL）。在3种类型的扫描仪中，主要使用II型，因为这种类型提供的图像最清晰，而且II型也易于操作。 TypeII即基底节。与传统5 MHz电子实时线性扫描仪相比，Typell能更清晰地描绘异常甲状旁腺，并能检测到较小的脓肿或增生。与手术相比，评估了超声检查（US）、CT和RI的可预测性分别得出结论。术前检查6个甲状旁腺腺瘤和14个肥大的甲状旁腺。对于0.5g以下的4个甲状旁腺，US诊断准确率为75%，CT诊断准确率为50%，RI未检出腺体。对于0.5g~1.0g的6个甲状旁腺，US、CT、RI的预测准确率为50%，CT为17%，RI为33%。对于1.0g以上的10个甲状旁腺，US、CT、RI的诊断准确率达90%分别为 ,70% 和 70%。 US 的总体敏感性高于 CT 和 RI。超声、CT、RI可检测到的甲状旁腺最小重量分别为150mg、150mg、500mg。术中超声未清晰显示甲状旁腺。同样，超声引导下经皮甲状旁腺活检也不成功。