Pathogenesis of Chronic Skin Ulcers by anti-HLA Class II/Misfolded Protein Complex Antibodies

抗 HLA II 类/错误折叠蛋白复合物抗体对慢性皮肤溃疡的发病机制

• 批准号: 18K08296
• 负责人: Arase Noriko
• 金额: $ 2.91万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2018
• 资助国家: 日本
• 起止时间: 2018-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-18K08296/
• 关键词: 抗Ro52/IgG/HLA-クラスII複合体抗体; Ro52; 皮膚筋炎; 抗MDA5抗体; 抗合成酵素抗体; Ro52/IgG/HLA-クラスII複合体; 抗MDA5抗体陽性無筋炎型皮膚筋炎; 抗合成酵素抗体症候群; KL-6; 皮膚潰瘍; 抗ARS抗体症候群; 間質性肺炎; 筋症状; 細胞質内蛋白; HLA Class II; ミスフォールド蛋白; β2GPI; 自己免疫; 自己免疫疾患; HLA-DR; 抗リン脂質抗体症候群; 自己抗体

项目成果

A Case of Pretibial Epidermolysis Bullosa with Novel Mutations of the COL7A1 Gene.

• DOI: 10.5021/ad.2022.34.1.81
• 发表时间: 2022-03
• 期刊: Annals of dermatology
• 影响因子: 1.6
• 作者: Shimizu Y;Kotobuki Y;Arase N;Arase H;Katayama I;Fujimoto M
• 通讯作者: Fujimoto M

Case of granuloma annulare after using tocilizumab

使用托珠单抗后出现环状肉芽肿一例

• DOI: 10.1111/1346-8138.15252
• 发表时间: 2020
• 期刊: JOURNAL OF DERMATOLOGY
• 影响因子: 3.1
• 作者: Hanaoka Yuma;Tanemura Atsushi;Takafuji Madoka;Kiyohara Eiji;Arase Noriko;Suzuki Osamu;Isohashi Fumiaki;Ogawa Kazuhiko;Fujimoto Manabu;[Kurumi Katsuda,Noriko Arase,Yukinobu Nakagawa,Atsushi Tanemura,Manabu Fujimoto]
• 通讯作者: [Kurumi Katsuda,Noriko Arase,Yukinobu Nakagawa,Atsushi Tanemura,Manabu Fujimoto]

Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.

• DOI: 10.1126/sciadv.abj9867
• 发表时间: 2022-03-04
• 期刊: Science advances
• 影响因子: 13.6
• 作者: Jin H;Kishida K;Arase N;Matsuoka S;Nakai W;Kohyama M;Suenaga T;Yamamoto K;Sasazuki T;Arase H
• 通讯作者: Arase H

Use of a combination of oral psoralen, ultraviolet A and interferon-gamma for the treatment of mycosis fungoides during pregnancy, which probably evoked CD8(+)CD30(+)lymphoproliferative disorder

联合使用口服补骨脂素、紫外线 A 和干扰素-γ 治疗妊娠期蕈样肉芽肿，可能诱发 CD8( )CD30( ) 淋巴增殖性疾病

• DOI: 10.1111/1346-8138.15628
• 发表时间: 2021
• 期刊: JOURNAL OF DERMATOLOGY
• 影响因子: 3.1
• 作者: Kishikawa Toshihiro;Arase Noriko;Tsuji Shigeyoshi;Maeda Yuichi;Nii Takuro;Hirata Jun;Suzuki Ken;Yamamoto Kenichi;Masuda Tatsuo;Ogawa Kotaro;Ohshima Shiro;Inohara Hidenori;Kumanogoh Atsushi;Fujimoto Manabu;Okada Yukinori;[Saki Iga,Atsushi Tanemura,Takumi Kamitani,Madoka Takafuji,Yuma Hanaoka,Noriko Arase,Manabu Fujimoto];[Kenji Tanimura,Shigeru Saito,Mikiya Nakatsuka,Takeshi Nagamatsu,Tomoyuki Fujii,Atsushi Fukui,Yuki Sasagawa,Masashi Deguchi,Noriko Arase,Hisashi Arase,Hideto Yamada];[Kyoko Tonomura,Eiji Kiyohara,Yuya Nakanishi,Atsushi Tanemura,Noriko Arase,Yukinobu Nakagawa,Manabu Fujimoto]
• 通讯作者: [Kyoko Tonomura,Eiji Kiyohara,Yuya Nakanishi,Atsushi Tanemura,Noriko Arase,Yukinobu Nakagawa,Manabu Fujimoto]

The beneficial effect of a PDE4 inhibitor in a patient with juvenile-onset intractable pityriasis rubra pilaris without CARD14 mutation

PDE4 抑制剂对无 CARD14 突变的青少年发病的顽固性毛发红糠疹患者的有益作用

• DOI: 10.1111/dth.14714
• 发表时间: 2021
• 期刊: DERMATOLOGIC THERAPY
• 影响因子: 3.6
• 作者: Kishikawa Toshihiro;Arase Noriko;Tsuji Shigeyoshi;Maeda Yuichi;Nii Takuro;Hirata Jun;Suzuki Ken;Yamamoto Kenichi;Masuda Tatsuo;Ogawa Kotaro;Ohshima Shiro;Inohara Hidenori;Kumanogoh Atsushi;Fujimoto Manabu;Okada Yukinori;[Saki Iga,Atsushi Tanemura,Takumi Kamitani,Madoka Takafuji,Yuma Hanaoka,Noriko Arase,Manabu Fujimoto];[Kenji Tanimura,Shigeru Saito,Mikiya Nakatsuka,Takeshi Nagamatsu,Tomoyuki Fujii,Atsushi Fukui,Yuki Sasagawa,Masashi Deguchi,Noriko Arase,Hisashi Arase,Hideto Yamada];[Kyoko Tonomura,Eiji Kiyohara,Yuya Nakanishi,Atsushi Tanemura,Noriko Arase,Yukinobu Nakagawa,Manabu Fujimoto];[Emi Inoue,Noriko Arase,Yuma Hanaoka,Atsushi Tanemura,Manabu Fujimoto]
• 通讯作者: [Emi Inoue,Noriko Arase,Yuma Hanaoka,Atsushi Tanemura,Manabu Fujimoto]