Clinical neuropathological study on the associated neurological/psychiatric symptoms and the responsible lesion in argyria granule dementia

银颗粒性痴呆相关神经/精神症状及致病病变的临床神经病理学研究

• 批准号: 19K07988
• 负责人: Saito Yuko
• 金额: $ 2.75万
• 依托单位: Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology (2020-2022)National Center of Neurology and Psychiatry (2019)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2019
• 资助国家: 日本
• 起止时间: 2019-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19K07988/
• 关键词: パーキンソニズム; タウオパチー; 高齢者; 認知症; 嗜銀顆粒; 脳幹; 線条体; タウ; 黒質; 精神症状; 嗜顆粒性疾患; 嗜銀顆粒性疾患; うつ; 縫線核; 気分障害; 神経病理; ステージング

项目成果

piRNA/PIWI Protein Complex as a Potential Biomarker in Sporadic Amyotrophic Lateral Sclerosis

piRNA/PIWI 蛋白复合物作为散发性肌萎缩侧索硬化症的潜在生物标志物

• DOI: 10.1007/s12035-021-02686-2
• 发表时间: 2022
• 影响因子: 5.1
• 作者: Abdelhamid Rehab F.;Ogawa Kotaro;Beck Goichi;Ikenaka Kensuke;Takeuchi Eriko;Yasumizu Yoshiaki;Jinno Jyunki;Kimura Yasuyoshi;Baba Kousuke;Nagai Yoshitaka;Okada Yukinori;Saito Yuko;Murayama Shigeo;Mochizuki Hideki;Nagano Seiichi
• 通讯作者: Nagano Seiichi

Soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for differential diagnosis of mild cognitive impairment

脑脊液中可溶性 APP-α 和 APP-β 作为鉴别诊断轻度认知障碍的潜在生物标志物

• DOI: 10.1007/s40520-021-01935-7
• 发表时间: 2022
• 影响因子: 4
• 作者: Araki W; Kanemaru K; Hattori K; Tsukamoto T; Saito Y; Yoshida S; Takano H; Sakata M; Yokoi Y; Omachi Y; Nagaoka U; Nagao M; Komori T; Tachimori H; Murayama S; Mizusawa H.
• 通讯作者: Mizusawa H.

Lewy pathology of the submandibular gland in Lewy body disease: A report of autopsy cases

路易体病下颌下腺的路易病理学：尸检病例报告

• DOI: 10.1111/neup.12772
• 发表时间: 2021
• 影响因子: 2.3
• 作者: Sakashita Yasuhiro;Matsubara Tomoyasu;Takata Tadayuki;Tanei Zen‐ichi;Motoda Atsuko;Yamazaki Mikihiro;Kawakami Ito;Sengoku Renpei;Saito Yuko;Arai Tomio;Yamada Masahito;Murayama Shigeo
• 通讯作者: Murayama Shigeo

Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions

神经元核内包涵体病中的霍纳蛋白沉积：直接鉴定包涵体中具有成分偏向区域的蛋白质

• DOI: 10.1186/s40478-022-01333-8
• 发表时间: 2022
• 影响因子: 7.1
• 作者: Park Hongsun;Yamanaka Tomoyuki;Toyama Yumiko;Fujita Atsushi;Doi Hiroshi;Nirasawa Takashi;Murayama Shigeo;Matsumoto Naomichi;Shimogori Tomomi;Ikegawa Masaya;Haltia Matti J.;Nukina Nobuyuki
• 通讯作者: Nukina Nobuyuki

Autopsy Validation of the Diagnostic Accuracy of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease

尸检验证¹²³I-间碘苄胍心肌闪烁显像对路易体病的诊断准确性

• DOI: 10.1212/wnl.0000000000200110
• 发表时间: 2022
• 影响因子: 9.9
• 作者: Matsubara Tomoyasu;Kameyama Masashi;Tanaka Noriko;Sengoku Renpei;Orita Makoto;Furuta Ko;Iwata Atsushi;Arai Tomio;Maruyama Hirofumi;Saito Yuko;Murayama Shigeo
• 通讯作者: Murayama Shigeo