Novel small molecule chemical compounds for promoting the differentiation efficiency of iPS-derived cardiomyocytes

促进 iPS 衍生心肌细胞分化效率的新型小分子化合物

• 批准号: 20K17129
• 负责人: Kishino Yoshikazu
• 金额: $ 2.66万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K17129/
• 关键词: 再生医療; ヒトiPS細胞由来心筋細胞; BMPシグナル; 心不全; 低分子化合物; iPS細胞; 心筋再生

项目成果

Scalable manufacturing of clinical-grade differentiated cardiomyocytes derived from humaninduced pluripotent stem cells for regenerative therapy

可大规模生产源自人类诱导多能干细胞的临床级分化心肌细胞，用于再生治疗

• DOI: 10.1111/cpr.13248
• 发表时间: 2022
• 影响因子: 8.5
• 作者: Yuika Morita; Yoshikazu Kishino; Keiichi Fukuda; Shugo Tohyama
• 通讯作者: Shugo Tohyama

The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in right ventricular failure

• DOI: 10.1038/s41467-022-33152-9
• 发表时间: 2022-09-15
• 期刊: Nature Communications
• 影响因子: 16.6
• 作者: S. Ito;H. Hashimoto;Hiroyuki Yamakawa;D. Kusumoto;Y. Akiba;Takahiro Nakamura;M. Momoi;Jin Komuro
• 通讯作者: Jin Komuro

Social Isolation and Implementation of Advanced Care Planning Among Hospitalized Patients With Heart Failure

心力衰竭住院患者的社会隔离和高级护理计划的实施

• DOI: 10.1161/jaha.122.026645
• 发表时间: 2022
• 影响因子: 5.4
• 作者: Kitakata Hiroki;Kohno Takashi;Kohsaka Shun;Fujisawa Daisuke;Nakano Naomi;Sekine Otoya;Shiraishi Yasuyuki;Kishino Yoshikazu;Katsumata Yoshinori;Yuasa Shinsuke;Fukuda Keiichi
• 通讯作者: Fukuda Keiichi

Apixaban-Associated Diffuse Alveolar Hemorrhage in an Elderly Man with Multiple Complications

患有多种并发症的老年男性与阿哌沙班相关的弥漫性肺泡出血

• DOI: 10.12659/ajcr.937809
• 发表时间: 2022
• 影响因子: 1.2
• 作者: Takuya Ozawa; Hideki Terai; Akiyoshi Kajino; Shiro Otake; Ayaka Saito; Miyuki Nishie; Yoshikazu Kishino; Hirofumi Kamata; Kentaro Hayashida; Makoto Ishii; Koichi Fukunaga
• 通讯作者: Koichi Fukunaga

Recurrence of Myopericarditis Following mRNA COVID-19 Vaccination in a Male Adolescent

男性青少年接种 mRNA COVID-19 疫苗后心肌心包炎复发

• DOI: 10.1016/j.cjco.2021.12.002
• 发表时间: 2022
• 作者: Umei Tomohiko C.;Kishino Yoshikazu;Watanabe Keiko;Shiraishi Yasuyuki;Inohara Taku;Yuasa Shinsuke;Fukuda Keiichi
• 通讯作者: Fukuda Keiichi