Development of a new treatment strategy for SLE by artificially restoring epigenomic memory in helper T cells

通过人工恢复辅助 T 细胞的表观基因组记忆开发 SLE 新治疗策略

基本信息

项目摘要

项目成果

期刊论文数量(4)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Involvement of lncRNA IL21-AS1 in interleukin-2 and T follicular regulatory cell activation in systemic lupus erythematosus.
  • DOI:
    10.1186/s13075-021-02682-w
  • 发表时间:
    2021-12-11
  • 期刊:
  • 影响因子:
    4.9
  • 作者:
    Hao H;Nakayamada S;Ohkubo N;Yamagata K;Zhang M;Shan Y;Iwata S;Zhang T;Tanaka Y
  • 通讯作者:
    Tanaka Y
Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases.
  • DOI:
    10.1186/s41232-021-00164-9
  • 发表时间:
    2021-05-03
  • 期刊:
  • 影响因子:
    8.1
  • 作者:
    Hao H;Nakayamada S;Tanaka Y
  • 通讯作者:
    Tanaka Y
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Nakayamada Shingo其他文献

Nailfold microvascular abnormalities are associated with a higher prevalence of pulmonary arterial hypertension in patients with MCTD
甲襞微血管异常与 MCTD 患者肺动脉高压患病率较高相关
  • DOI:
    10.1093/rheumatology/keac165
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    5.5
  • 作者:
    Todoroki Yasuyuki;Kubo Satoshi;Nakano Kazuhisa;Miyazaki Yusuke;Ueno Masanobu;Satoh-Kanda Yurie;Kanda Ryuichiro;Miyagawa Ippei;Hanami Kentaro;Nakatsuka Keisuke;Saito Kazuyoshi;Nakayamada Shingo;Tanaka Yoshiya
  • 通讯作者:
    Tanaka Yoshiya
A Case of Simultaneous Onset of Highly Active Systemic Lupus Erythematosus and IgG4-Related Renal Disease
高度活动性系统性红斑狼疮与IgG4相关肾病同时发病1例
  • DOI:
    10.1093/mrcr/rxac002
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    0.8
  • 作者:
    Fujita Yuya;Iwata Shigeru;Nakano Kazuhisa;Nakayamada Shingo;Miyazaki Yusuke;Kawabe Akio;Korekoda-Yoshinari Hiroko;Nawata Aya;Tanaka Yoshiya
  • 通讯作者:
    Tanaka Yoshiya
Type I and II interferons commit to abnormal expression of chemokine receptor on B cells in patients with systemic lupus erythematosus
I型和II型干扰素导致系统性红斑狼疮患者B细胞上趋化因子受体的异常表达
  • DOI:
    10.1016/j.clim.2018.12.017
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    8.6
  • 作者:
    Yoshikawa Maiko;Nakayamada Shingo;Kubo Satoshi;Nawata Aya;Kitanaga Yukihiro;Iwata Shigeru;Sakata Kei;Ma Xiaoxue;Wang Sheau Pey;Nakano Kazuhisa;Saito Kazuyoshi;Tanaka Yoshiya
  • 通讯作者:
    Tanaka Yoshiya
Radiological patterns of pulmonary involvement may predict treatment response in rheumatoid arthritis: A retrospective study
肺部受累的放射学模式可以预测类风湿关节炎的治疗反应:一项回顾性研究
  • DOI:
    10.1016/j.resinv.2018.12.006
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    3.1
  • 作者:
    Hanaka Tetsuya;Kido Takashi;Ishimoto Hiroshi;Oda Keishi;Noguchi Shingo;Nawata Aya;Nakayamada Shingo;Sakamoto Noriho;Tanaka Yoshiya;Yatera Kazuhiro;Mukae Hiroshi
  • 通讯作者:
    Mukae Hiroshi
mTOR activation in CD8+ cells contributes to disease activity of rheumatoid arthritis and increases therapeutic response to TNF inhibitors
CD8 细胞中的 mTOR 激活有助于类风湿性关节炎的疾病活动并增加对 TNF 抑制剂的治疗反应
  • DOI:
    10.1093/rheumatology/keab834
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    5.5
  • 作者:
    Zhang Mingzeng;Iwata Shigeru;Sonomoto Koshiro;Ueno Masanobu;Fujita Yuya;Anan Junpei;Miyazaki Yusuke;Ohkubo Naoaki;Sumikawa Maiko Hajime;Todoroki Yasuyuki;Miyata Hiroko;Nagayasu Atsushi;Kanda Ryuichiro;Hao He;Trimova Gulzhan;Lee Seunghyun;Nakayamada Shingo
  • 通讯作者:
    Nakayamada Shingo

Nakayamada Shingo的其他文献

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{{ truncateString('Nakayamada Shingo', 18)}}的其他基金

Dynamism of T helper cells in systemic lupus erythematosus
系统性红斑狼疮中 T 辅助细胞的动态
  • 批准号:
    17K10010
  • 财政年份:
    2017
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Diversity of T follicular helper cells in the pathogenesis of systemic autoimmune diseases
滤泡辅助T细胞在系统性自身免疫性疾病发病机制中的多样性
  • 批准号:
    26461496
  • 财政年份:
    2014
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

相似海外基金

Development of prophylaxis and therapeutics for autoimmune gastritis targeting gastric mucosa-associated microbiota and follicular regulatory T cell
针对胃粘膜相关微生物群和滤泡调节性 T 细胞开发自身免疫性胃炎的预防和治疗方法
  • 批准号:
    22K08040
  • 财政年份:
    2022
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The analysis of T follicular helper and regulatory cells of patients with atopic asthma comorbid with allergic rhinitis by treated with HDM-SLIT
HDM-SLIT治疗特应性哮喘合并变应性鼻炎患者滤泡辅助T及调节细胞分析
  • 批准号:
    21K08441
  • 财政年份:
    2021
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The influence of T follicular helper and T follicular regulatory cells on colorectal cancer
滤泡辅助T细胞和滤泡调节T细胞对结直肠癌的影响
  • 批准号:
    19K17498
  • 财政年份:
    2019
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
Analysis of T follicular helper cells and B regulatory cells in patients with asthma comorbid with rhinitis by HDM-mites SLIT
HDM-mites SLIT 分析哮喘合并鼻炎患者滤泡辅助性 T 细胞和调节性 B 细胞
  • 批准号:
    18K08391
  • 财政年份:
    2018
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Novel Therapeutic Strategies for Birch Pollinosis by Targeting Functional Lymphocytes
针对功能性淋巴细胞的桦树花粉病新治疗策略
  • 批准号:
    18K16898
  • 财政年份:
    2018
  • 资助金额:
    $ 2.83万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
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