Planning: PREC: Improved Properties and Additive Manufacturing of Hydrogels

规划：PREC：水凝胶性能的改进和增材制造

• 批准号: 2335012
• 负责人: Juana Mendenhall
• 金额: $ 20万
• 依托单位: Morehouse College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-11-15 至 2025-10-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2335012&HistoricalAwards=false
• 关键词: Planning; PREC; Improved; Properties; Additive

In this planning grant, funded by the Chemistry Division at NSF, Professor Juana Mendenhall of Morehouse College will work with Professor Stephen Craig at Duke University’s NSF Center for the Chemistry of Molecularly Optimized Networks (MONET) to develop a partnership that could form the basis of a future submission to the ‘Partnerships for Research and Education in Chemistry (PREC)’ program. This collaboration will provide an opportunity for training primarily African American students to learn three-dimensional (3D) printing and new chemistries to improve their mechanical properties in hydrogels. In partnership with MONET, the PREC planning grant will support new educational offerings in chemistry by developing new chemistry courses using MONET-based research tools and hosting technical workshops. This PREC planning grant will also establish a broader community of Historically Black Colleges and Universities (HBCUs) researchers and minority trainees conducting research in macromolecular chemistry and support educational outreach for K-12 students in the metro Atlanta area. Using Additive Manufacturing as a tool to improve hydrogel three-dimensional (3D) structures with precise architecture at various scales will continue to expand over the years. This PREC planning grant will leverage the MONET expertise to study chemical strategies to improve the structure and function of hydrogels. Thrust One aims to develop mechanically robust hydrogels using crosslinking chemistries to improve hydrogel use in tissue engineering applications. Thrust Two will support improving the chemistries of 3D printed scaffolds using mechanophores to create robust 3D scaffolds. Thrust three will guide the synthesis of interpenetrating double-network composite hydrogels containing hyaluronic acid to produce more robust hydrogel networks. Morehouse College, a Historically Black Colleges and Universities (HBCU) that educates undergraduates of color, will partner with MONET to expand knowledge in additive manufacturing of hydrogels by varying feedstock ratios and crosslinking chemistries. This partnership will establish a network of HBCU researchers with macromolecular chemistry expertise, developing cross-disciplinary chemistry courses using MONET resources and hosting K-12 science outreach activities for the broader metro Atlanta community.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在这项由 NSF 化学部资助的规划拨款中，莫尔豪斯学院的 Juana Mendenhall 教授将与杜克大学 NSF 分子优化网络化学中心 (MONET) 的 Stephen Craig 教授合作，建立合作伙伴关系，为以下项目奠定基础：未来将提交给“化学研究和教育伙伴关系 (PREC)”计划。此次合作将为主要培训非裔美国学生提供学习三维 (3D) 打印和技术的机会。 PREC 规划赠款将与 MONET 合作，通过使用基于 MONET 的研究工具开发新的化学课程并举办技术研讨会来支持新的化学教育课程。由传统黑人学院和大学 (HBCU) 研究人员和少数族裔实习生组成的更广泛社区，开展大分子化学研究，并支持亚特兰大都会地区 K-12 学生的教育推广，使用增材制造作为改进水凝胶的工具。具有不同尺度的精确架构的三维 (3D) 结构将在未来几年继续扩展，PREC 的规划拨款将利用 MONET 的专业知识来研究化学策略，以改善水凝胶的结构和功能，旨在开发机械坚固的水凝胶。使用交联化学物质来改善水凝胶在组织工程应用中的使用，推力二将支持使用力力团改进 3D 打印支架的化学物质，以创建坚固的 3D 支架。将指导含有透明质酸的互穿双网络复合水凝胶的合成，以产生更强大的水凝胶网络，莫尔豪斯学院是一所教育有色人种本科生的历史悠久的黑人学院和大学 (HBCU)，将与 MONET 合作扩展增材制造的知识。通过改变原料比例和交联化学来制备水凝胶 这种合作伙伴关系将建立一个具有大分子化学专业知识的 HBCU 研究人员网络，利用 MONET 资源和托管开发跨学科化学课程。针对更广泛的亚特兰大都会社区的 K-12 科学推广活动。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。