North Carolina Center for Coastal Algae, People, and Environment NC-CAPE

北卡罗来纳州沿海藻类、人类和环境中心 NC-CAPE

• 批准号: 2414792
• 负责人: Astrid Schnetzer
• 金额: $ 406.67万
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-02-01 至 2029-01-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2414792&HistoricalAwards=false
• 关键词: North; Carolina; Center; Coastal; Algae

The North Carolina Center for Coastal Algae, People, and Environment (NC C-CAPE) is a five-year effort to advance our scientific knowledge on the risks of harmful algal blooms (HABs) in NC coastal waters, including the United States’ largest lagoonal estuary, the Pamlico-Albemarle Sound System. Concerns about emergent HABs in the region have surged and coincide with reports on toxins present in water and seafood. Major knowledge gaps currently exist on environmental drivers that lead to the development of these blooms and the production of toxins, and associated human health risks. With growing threats to ecosystem and human health, with the increasing frequency, intensity, and range of cyanobacterial blooms, attributable to eutrophication and likely exacerbated by climate change, NC-CAPE will provide data to guide efforts to implement effective monitoring approaches, inform guideline values for safe consumption of water and seafood, deliver predictive tools to assess emergent and future toxin exposure risk, and leverage community engagement initiatives to fill data gaps and improve oceans and human health. NC C-CAPE will provide investigators at all career stages valuable opportunities for collaboration, leadership, cross-training, as well as the foundational support to expand their research programs across disciplinary boundaries. The Center’s Community Engagement Core will use principles of data justice, which is central to understanding and addressing HAB exposure and prevention, to empower community members as experts with the capacity to conduct critical and systemic inquiry into their own lived experiences. The Center is committed to recruiting students, postdocs, and staff from diverse backgrounds including underrepresented groups, and will convene an External Advisory Committee that reflects the diversity of stakeholders. Activities will include the establishment of a data justice charter with community groups and the establishment of a Community Advisory Board to ensure stakeholder involvement in problem definition, design, and data dissemination. The Center is jointly supported by NSF’s Division of Ocean Sciences and by the National Institute for Environmental Health Sciences (NIEHS).NC C-CAPE combines multidisciplinary expertise in ocean and climate science, toxicology, epidemiology, modeling, and community engagement to understand, predict, and reduce risks to human health from cyanobacterial HABs in coastal waters. The Center comprises three research projects, bound together through the Center Administration and Community Engagement cores. NC C-CAPE will elucidate links among environmental drivers and HAB dynamics, microcystin congener composition, and toxin contamination in oysters and blue crabs (Project 1), define how MC mixtures influence mechanisms of liver toxicity and resulting risk of adverse health outcomes in regulatory-relevant mammalian models as well as at-risk human populations (Project 2), and integrate diverse data sets and coastal circulation modeling within a probabilistic modeling framework to elucidate environmental controls on microcystin distribution in water and seafood and assess exposure risk in a changing climate (Project 3). Finally, the Center’s Community Engagement Core will promote the translation of Center discoveries, use the principles of data justice to elevate community voices in research design, fill gaps in HAB exposure and prevention knowledge relevant to environmental justice, and support critical and systemic inquiry led by community partners.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

北卡罗来纳州沿海藻类，人和环境（NC C-CAPE）的北卡罗来纳州中心是为期五年的努力，旨在提高我们在NC沿海水域中有害藻类血液（HAB）风险的科学知识，其中包括美国最大的Lagoonal河口Pamlico-Albemarle Sound System。对该地区新兴HAB的担忧激增并与水和海鲜中存在的毒素有关。目前存在着有关环境驱动因素的主要知识差距，从而导致这些血液的发展以及毒素的产生以及相关的人类健康风险。随着对生态系统和人类健康的日益增长，随着C氰基血液的频率，强度和范围的越来越多，可归因于富营养化，可能会因气候变化而加剧，NC-CAPE将提供数据，以指导有效的监视方法，以实施有效的监视方法，以确保良好的启动和预测工具，以提供预测的水平，并提供预测的水平，并提供范围的范围，并提供效果，并提供效果和未来的效果，并提供了未来的效果，并提供了未来的效果，并提供了未来的范围，并提供了未来的效果，并提供了未来的效果，并提供了未来的效果。差距并改善海洋和人类健康。 NC C-CAPE将在所有职业阶段为调查人员提供合作，领导，交叉培训以及基础支持的宝贵机会，以扩展其研究计划跨学科界限。该中心的社区参与核心将使用数据正义原则，这对于理解和解决HAB暴露和预防是核心，以使社区成员成为有能力对自己的生活经验进行关键和系统性探究的专家。该中心致力于招募来自包括代表性不足的团体在内的不同背景的学生，博士后和员工，并将召集一个反映利益相关者多样性的外部咨询委员会。活动将包括建立与社区团体的数据正义宪章以及建立社区咨询委员会，以确保利益相关者参与问题的定义，设计和数据传播。该中心由NSF海洋科学系和美国国家环境健康科学研究所（NIEHS）共同支持。NCC-CAPE结合了海洋和气候科学，毒理学，流行病学，建模和社区互动，以了解，预测和降低Cyanobactial Waters的人类健康的风险，以了解，预测和降低风险的风险。该中心由三个研究项目组成，通过中心管理和社区参与核心结合在一起。 NC C-CAPE will elucidate links among environmental drivers and HAB dynamics, microcystin congener composition, and toxin contamination in oysters and blue crabs (Project 1), define how MC mixtures influence mechanisms of liver toxicity and resulting risk of adverse health outcomes in regulatory-relevant mammalian models as well as at-risk human populations (Project 2), and integrated divers data sets and概率建模框架内的沿海循环建模，以阐明水和海鲜中微囊蛋白藻分布的环境控制，并在不断变化的气候下评估暴露风险（项目3）。最后，该中心的社区参与核心将促进中心发现的翻译，利用数据正义的原则来提升社区的研究设计，填补与环境正义相关的HAB暴露和预防知识的空白，并支持由社区合作伙伴领导的关键和系统的询问。该奖项通过评估了NSF的批评，反映了NSF的审查，这反映了众所周知的Intellia Infectia Intellia Infactia Intelliquia inftimial the Internitial and Founditial的基础和基础。