I-Corps: Digital Device to Improve the Safety of Extraventricular and Lumbar Cerebral Spinal Fluid Drainage

I-Corps：提高脑室外和腰椎脑脊液引流安全性的数字设备

• 批准号: 2320994
• 负责人: Joshua Medow
• 金额: $ 5万
• 依托单位: University of Wisconsin-Madison
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2024-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2320994&HistoricalAwards=false
• 关键词: Corps; Digital; Device; Improve; Safety

The broader impact/commercial potential of this I-Corps project is the development of a reusable management system and disposable tubing that may cut current costs while improving the standard of care by reducing patient discomfort, reducing medical errors associated with extraventricular and lumbar drain use, and reducing nursing management time. Extraventricular and lumbar drain systems are used in approximately 60,000 patients annually in the US with a market of $1.04B in 2021. The research team has performed discovery interviews with neurosurgeons and ICU nurses, which have validated the need for customizable drainage control and improved management efficiency. The postoperative management of extraventricular and lumbar drains is primarily a nursing responsibility, consisting of hourly checks and manual releveling whenever patients change position. The use of conventional extraventricular drains add significantly to a nurse’s workload, especially since they are mandated to ensure close supervision with a nurse-to-patient ratio of 1:2. To improve the state-of-the-art, this technology takes continuous pressure measurements, compensates for patient movement to minimize discomfort and harm to patients from over or underdrainage, provides far more customizable control for patient optimization, and uses a much less expensive disposable.This I-Corps project is based on the development of an external cerebrospinal fluid drainage system that provides customizable drainage control for neurosurgeons, requires less intervention by nurses, and makes cerebrospinal fluid drainage safer for patients. The device in development is used to drain cerebrospinal fluid from the brain via an extraventricular drain or from the spine via a lumbar drain, and to aid in the diagnosis and treatment of elevated intracranial pressure. State-of-the art drainage systems connect to an existing ventricular or lumbar catheter that has been placed by a neurosurgeon to drain cerebrospinal fluid and measure pressure using a hospital’s existing standard pressure transducer. This technology’s disposable tubing line connects to existing brain and spine catheters and pressure transducers using industry standard Luer locks. The technology and its disposable parts are never placed inside humans. The sterile disposable tubing is manually secured to the technology’s controller system externally. The closed drainage system is not disrupted, limiting infection risk to the patient.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该 I-Corps 项目更广泛的影响/商业潜力是开发可重复使用的管理系统和一次性管道，可以降低当前成本，同时通过减少患者不适、减少与室外和腰椎引流使用相关的医疗错误来提高护理标准，并减少护理管理时间。美国每年约有 60,000 名患者使用脑室外和腰椎引流系统，2021 年市场规模为 $1.04B。研究团队进行了发现访谈。与神经外科医生和 ICU 护士合作，验证了可定制引流控制和提高管理效率的必要性。脑室外引流和腰椎引流的术后管理主要是护理责任，包括每小时检查和每当患者改变体位时进行手动重新调平。脑室外引流显着增加了护士的工作量，特别是因为他们必须确保护士与病人的比例为 1:2 的密切监督。为了提高最先进的技术，这项技术。进行连续的压力测量，补偿患者的移动，以最大程度地减少排水过度或排水不足对患者造成的不适和伤害，为患者优化提供更多可定制的控制，并使用更便宜的一次性产品。这个 I-Corps 项目基于开发外部脑脊液引流系统，为神经外科医生提供可定制的引流控制，需要较少的护士干预，并使脑脊液引流对患者更安全。正在开发的设备用于从大脑中引流脑脊液。通过脑室外引流或通过腰椎引流从脊柱排出，并帮助诊断和治疗颅内压升高。最先进的引流系统连接到由神经外科医生放置的现有心室或腰椎导管。使用医院现有的标准压力传感器排出脑脊液并测量压力。该技术的一次性管路使用行业标准鲁尔锁连接到现有的脑部和脊柱导管和压力传感器。技术及其一次性部件永远不会放置在人体内。无菌一次性管道被手动固定到该技术的控制器系统外部，不会破坏封闭的引流系统，从而限制了患者的感染风险。该奖项反映了 NSF 的法定使命，并被视为是。值得通过使用基金会的智力优点和更广泛的影响审查标准进行评估来支持。