Equipment:MRI Track 2 Acquisition of a 3D X-ray microscope for advanced specimen-based organismal research

设备：MRI Track 2 购买 3D X 射线显微镜，用于先进的基于标本的有机体研究

• 批准号: 2320473
• 负责人: Roger Benson
• 金额: $ 213.96万
• 依托单位: American Museum Natural History
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2320473&HistoricalAwards=false
• 关键词: Equipment; MRI; Track; Acquisition; 3D; Equipment; MRI; Track; Acquisition; 3D

This Major Research Instrumentation (MRI) award will provide funds to acquire an X-ray microscope to support cutting-edge research at the American Museum of Natural History (AMNH) in New York. With over 170 working scientists, the AMNH is a globally-leading research institution for the study of organismal structure, function, systematics, and evolution, as well as anthropology and the Earth and planetary sciences. The X-ray microscope is a next-generation imaging device that allows visualization of the internal structure of objects, resolving features as small as one-thousandth of a millimeter. This instrument will allow high resolution 3D visualization of AMNH’s world-class natural history collections, which includes 34 million scientific objects, primarily biological, fossil, and geological specimens. The resulting research will yield significant advancements across a wide range of topics, including the anatomy, evolution, growth, development, and function of organisms, as well as climate change and the evolution of planetary systems, across the fields of paleontology, zoology, archaeology, ethnology, oceanography, and mineralogy. The new instrument will contribute to training of the next generation of scientists via the Richard Gilder Graduate School and affiliated programs (e.g., City University of New York, New York University, Columbia University). It will increase accessibility of AMNH specimens by allowing online sharing of digital data. It will also contribute to exhibition and public educational programs by generating superb 3D visualizations of important specimens, including minute details of tiny insects and fossil specimens that cannot be extracted from the rocks they were preserved in.The 630 Versa X-ray microscope (XRM) is a micro- to nano-computed tomography (CT) system with capabilities that are critical to the next-generation of specimen-based research, including sub-micron resolution (true spatial resolution down to 0.5 µm), high X-ray flux allowing faster throughput and increased scan quality, and propagation phase-contrast to enhance edge-detection and the distinctions between structures of similar densities for low-absorbing materials. This instrument will extend the frontiers of specimen-based research by significantly increasing achievable scan resolution and the quality of scans that can be obtained at high resolutions within a wide range of intact specimen sizes. The instrument will provide an important resource for researchers at the AMNH as well as affiliated researchers across other institutions and consortia in the New York City region. It will stimulate the next generation of discoveries by expanding the frontiers of our research and training across a wide user base. It will directly contribute to research programs across a wide range of topics including the origins and early evolution of mammalian anatomy and physiology, diversification of arthropods, skeletal function of extinct hominins, effects of ocean acidification on marine organisms, processes of solar system formation, the tracheal system of insects, microstructural anatomy of animal tissues, the functional morphology of small-bodied vertebrates including bats and fishes, and many others.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项主要的研究工具（MRI）奖将为获得X射线显微镜提供资金，以支持纽约美国自然历史博物馆（AMNH）的尖端研究。 AMNH拥有170多名工作科学家，是一家全球领先的研究机构，用于研究有机结构，功能，系统学和进化以及人类学以及地球和行星科学的研究机构。 X射线显微镜是一种下一代成像设备，允许可视化对象的内部结构，从而解决了小至千分之一毫米的特征。该仪器将允许对AMNH世界一流的自然历史收集的高分辨率3D可视化，其中包括3400万个科学对象，一级生物学，化石和地质标本。最终的研究将在广泛的主题中取得重大进步，包括生物体的解剖学，进化，生长，发育和功能，气候变化以及行星系统的进化，跨古生物学，动物学，考古学，考古学，民族学，人种学，海洋学，海洋学和Mineraology。新工具将通过理查德·吉尔德（Richard Gilder）研究生院和会员计划（例如纽约市，纽约大学，纽约大学，哥伦比亚大学）对下一代科学家进行培训。通过允许在线共享​​数字数据，它将增加AMNH规格的可访问性。它还将通过产生重要规格的超级3D可视化来为展览和公共教育计划做出贡献，包括无法从其保存的岩石中提取的微小绝缘和化石规范的细节。630versa X射线显微镜（XRM）是与纳米相典型的（CT）相关的s型（CT），这些系统是与纳米相关的系统的重要性（CT），这些系统是近来的（CT）的至关重要的系统，这些系统是至关重要的。分辨率（真正的空间分辨率降至0.5 µm），高X射线通量，可以更快地吞吐量和增加扫描质量，并繁殖相位对比度，以增强边缘检测和低吸收材料的相似密度结构之间的区别。该仪器将通过显着提高可实现的扫描分辨率以及可以在整个完整标本大小范围内获得的高分辨率获得的扫描质量来扩展基于标本的研究的前沿。该工具将为AMNH的研究人员以及纽约市地区其他机构和财团的会员研究人员提供重要资源。它将通过扩展我们的研究和培训的前沿跨越广泛的用户群来刺激下一代发现。 It will directly contribute to research programs across a wide range of topics including The origins and early evolution of mammalian anatomy and physiology, diversification of arthropods, skeletal function of extinct hominins, effects of ocean acidification on marine organisms, processes of solar system formation, the tracheal system of insects, microstructural anatomy of animal tissues, the functional morphology of small-bodied vertebrates including bats and FISHES和许多其他人。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子优点和更广泛影响的审查标准来评估值得支持的。