Postdoctoral Fellowship: MPS-Ascend: Cyclodextrin-Poly(ethylene glycol)-Based Dynamic Covalent Networks

博士后奖学金：MPS-Ascend：基于环糊精聚乙二醇的动态共价网络

• 批准号: 2316707
• 负责人: Emmanuel Nsengiyumva
• 金额: $ 30万
• 依托单位: Nsengiyumva, Emmanuel M
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-15 至 2026-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2316707&HistoricalAwards=false
• 关键词: Postdoctoral; Fellowship; MPS; Ascend; Cyclodextrin; Postdoctoral; Fellowship; MPS; Ascend; Cyclodextrin

NON-TECHNICAL SUMMARY:This research, to be carried out at the University of Buffalo, is focused on societal aspects relevant to sustainability. It involves development and study of advanced polymeric materials whose molecules can form networks that can be broken and reconstituted dynamically ("dynamic covalent networks"). They can potentially offer high performance on flue gas separation and the removal of hazardous chemicals (including both industrial pollutants and harmful biomolecules) from aqueous systems. If successful, the research activities can impact chemistry, materials, membrane science, and biomedical science. The research results of this project will be disseminated through publications and presentations. Research participation of underrepresented undergraduate students will be arranged through the SUNY LSAMP program. The project will incorporate multifaceted educational efforts including outreach to help promote science education in Buffalo’s public schools which include many students from underrepresented groups.TECHNICAL SUMMARY:Cyclodextrin (CD)-based polymers are promising materials for membrane separation and other applications. Dynamic covalent polymer networks have also attracted considerable interest due to their self-healing and other remarkable properties. The core hypothesis of this project is that CD-based dynamic covalent polymer networks can serve as novel membrane materials with self-healing properties and significant separation performance. Accordingly, dynamic covalent networks with building units of β-CD (a representative form of CD) and poly(ethylene glycol) (PEG) chain linking with dynamic urethane bonds will be investigated in this project. The research objectives are: 1) to establish the synthetic approach to CD-PEG-based dynamic covalent networks, 2) to understand their structure-property relationships, and 3) to examine their applications for carbon dioxide (CO2) separation and removal of hazardous chemicals from aqueous phases. CD-PEG-methacrylate conjugates having dynamic urethane bonds will be prepared first and then photocured to give the CD-PEG-based dynamic covalent networks. Characterization and studies of physiochemical, mechanical and self-healing properties of the networks will be performed. Finally, membranes of CD-PEG-based covalent dynamic networks will be prepared for studies on CO2/N2 separation and removal of perfluorooctanoic acid, cholesterol, and uric acid from aqueous phase..This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

非技术摘要：这项在布法罗大学进行的研究重点是与可持续性有关的社会方面。它涉及对高级聚合物材料的开发和研究，这些聚合物材料的分子可以形成可以动态破坏和重组的网络（“动态共价网络”）。它们可能在烟气分离上提供高性能，并从水性系统中去除危险化学物质（包括工业污染物和有害生物分子）。如果成功，研究活动可能会影响化学，材料，膜科学和生物医学科学。该项目的研究结果将通过出版物和演示进行传播。 SUNY LSAMP计划将安排代表性不足的本科生的研究参与。该项目将纳入多方面的教育工作，包括宣传，以帮助促进布法罗公立学校的科学教育，其中包括来自代表性不足的小组的许多学生。技术摘要：基于基于的聚合物（CD）的聚合物是膜分离和其他应用的有希望的材料。动态共价聚合物网络也因其自我修复和其他出色的特性而引起了考虑的兴趣。该项目的核心假设是，基于CD的动态共价聚合物网络可以用作具有自我修复特性和显着分离性能的新型膜材料。彼此之间，将在该项目中研究具有β-CD（CD的代表形式）和聚乙二醇）链（PEG）链的动态共价网络。研究目标是：1）建立基于CD-PEG的动态共价网络的合成方法，2）了解它们的结构 - 培训关系，3）检查其对二氧化碳（CO2）分离的应用，并去除了从水相中的有害化学物质的危险化学物质。将首先准备具有动态氨基烷基键的CD-PEG - 丙烯酸酯偶联物，然后将其照射以获得基于CD-PEG的动态共价网络。将对网络的物理化学，机械和自我修复特性进行表征和研究。最后，将准备基于CD-PEG的共价动态网络的机制，以研究CO2/N2分离和去除全氟辛酸，胆固醇和尿酸与水相中的尿酸。该奖项反映了NSF的法规任务，并认为通过基金会的知识优点和广泛的critia criter critia criter criter criter critia criter critia criter critia criter criter criter criter criter critia criter criter critia criter critia criter critia criter criter criter criter criter criter criter apperiation。