REU Site: Comparative Animal Model Approaches to Regeneration and Aging

REU 网站：再生和衰老的比较动物模型方法

• 批准号: 2243416
• 负责人: Dustin Updike
• 金额: $ 40.97万
• 依托单位: Mount Desert Island Biological Laboratory
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2026-03-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2243416&HistoricalAwards=false
• 关键词: REU; Site; Comparative; Animal; Model

This REU Site award to the Mount Desert Island Biological Laboratory (MDIBL), located in Bar Harbor, ME, will support the training of 10 students for 10 weeks during the summers of 2023-2025. It is anticipated that a total of 30 students, primarily from schools with limited research opportunities or from underrepresented groups, will be trained in the program. Students will be at all stages of their undergraduate studies, and special consideration will be given to applicants interested in microscopy and comparative animal model research on regeneration and aging. Students will learn how research is conducted, and many will present the results of their work at scientific conferences. Assessment of the program will be done through the online SALG URSSA tool. Students will be required to register in the NSF ETAP system (etap.nsf.gov) and tracked after the program to determine their career paths.This REU program MDIBL will expose students to comparative animal model approaches used to understand the biology of regeneration and aging. Labs at this REU site are interested in how cells, tissues, organs, and limbs are repaired or replenished after injury or during the ordinary course of development and the mechanisms retained or reemployed to ensure an organism thrives once development is complete. To answer these questions, researchers at MDIBL use various animal models. These animals include zebrafish, killifish, axolotl, fruit flies (Drosophila), and nematodes (Caenorhabditis elegans), which can be used to compare the genetic similarities and differences in aging and regeneration strategies across species. Students will be fully integrated into the scientific culture of MDIBL through symposia, seminars, activities, responsible conduct of research training, and weekly career discussions. Students More information about the program is available in the NSF ETAP registration system and by visiting https://mdibl.org/education/student-fellowships/reu-summer-fellowships/, or by contacting the PI (Dr. Updike at [e-mail]) or the co-PI (Dr. Disney at [e-mail]).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项授予位于ME Bar Harbour的Mount Desert Island生物实验室（MDIBL）的REU现场奖，将在2023 - 2025年的夏季支持10个学生的培训10周。预计将在该计划中培训总共30名学生，主要来自研究机会有限的学校或来自代表性不足的群体的学校。学生将处于本科学习的各个阶段，并将特别考虑对显微镜和比较动物模型对再生和衰老的比较研究。学生将学习如何进行研究，许多人会在科学会议上介绍他们的工作结果。该程序的评估将通过在线Salg Urssa工具进行。学生将被要求在NSF ETAP系统（ETAP.NSF.GOV）中注册，并在计划之后进行跟踪以确定其职业道路。该计划MDIBL将使学生接触到用于了解再生和衰老生物学的比较动物模型方法。此REU站点的实验室对细胞，组织，器官和四肢受伤后或在普通发展过程中如何修复或补充的细胞，组织，器官和肢体以及保留或重新就业的机制如何维修或补充，以确保有机体在发育完成后蓬勃发展。为了回答这些问题，MDIBL的研究人员使用各种动物模型。这些动物包括斑马鱼，Killifish，Axolotl，果蝇（果蝇）和线虫（秀丽隐杆线虫），可用于比较物种跨物种的遗传相似性和遗传相似性和差异。通过研讨会，研讨会，活动，负责任的研究培训和每周职业讨论，学生将完全融入MDIBL的科学文化中。学生可以在NSF ETAP注册系统中获得有关该计划的更多信息，并通过访问https://mdibl.org/education/student-fellowships/reu-summer-fellowships/一下，或通过与pi（[e-mail]）或dissney（dissney the jdiisney ndiesney nderney the jdi inderive the jdi necriffere the jdi necrifferciply the [e-mail]）联系PI（updike）。 NSF的法定使命，并使用基金会的知识分子优点和更广泛的影响审查标准来评估值得支持。