MRI: Acquisition of a Gel Permeation Chromatography System with Dynamic Light Scattering Capabilities to Advance Research and Instructional Activities at Murray State University

MRI：采购具有动态光散射功能的凝胶渗透色谱系统，以推进默里州立大学的研究和教学活动

• 批准号: 2215040
• 负责人: Kevin Miller
• 金额: $ 22.36万
• 依托单位: Murray State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2025-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2215040&HistoricalAwards=false
• 关键词: MRI; Acquisition; Gel; Permeation; Chromatography

This award is jointly supported by the Major Research Instrumentation, the Established Program to Stimulate Competitive Research (EPSCoR), and the Chemistry Research Instrumentation Programs. Murray State University is acquiring a gel permeation chromatography system with dynamic light scattering detection (GPC/DLS) to support the research of Professor Kevin Miller and colleagues Gary Stinchcomb, Bikram Subedi, Christopher Lennon, and Grace Eder. This instrument facilitates research in the areas of chemistry, biological sciences, and Earth and environmental sciences. GPC separates molecules as a function of size based on their elution from a packed column. DLS is subsequently used, in-line, to measure time-dependent fluctuations in scattered light, which is related to molecular diffusion coefficeints and their size distributions. This instrument enhances the educational, research, and teaching efforts of students at all levels in many departments as well as provides accessibility for use at nearby institutions. The instrument is leveraged in research training opportunities in polymer chemistry, molecular biology, and environmental science. Students gain hands-on experience with the instrument through its integration in various courses.The award of the GPC/DLS is aimed at enhancing research and education at all levels, especially in areas such as polymer chemistry, molecular biology, and environmental science. Research focuses on molecular weight analysis of ionenes and cellulose functionalized with ionic liquids and poly(ionic liquids). Other investigations include the separation and analysis of drug residues and other small molecules from biological tissue, environmental samples, and wastewater. It also assists in analyzing molecular weight distributions of copolymers for organic photovoltaics.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要的研究工具，既定的竞争研究计划（EPSCOR）和化学研究工具计划共同支持。默里州立大学（Murray State University）正在购买具有动态光散射检测（GPC/DLS）的凝胶渗透色谱系统，以支持Kevin Miller教授和同事Gary Stinchcomb，Bikram Subedi，Christopher Lennon和Grace Eder的研究。该仪器促进了化学，生物科学以及地球和环境科学领域的研究。 GPC根据大小从包装柱中的洗脱而分离分子。随后使用DLS在线使用散射光中的时间依赖性波动，这与分子扩散系数及其大小分布有关。该工具增强了许多部门各级学生的教育，研究和教学工作，并为附近机构提供了可访问性。该仪器在聚合物化学，分子生物学和环境科学的研究培训机会中杠杆作用。学生通过将其在各种课程的集成中获得动手实践经验。GPC/DLS的奖励旨在增强各个级别的研究和教育，尤其是在聚合物化学，分子生物学和环境科学等领域。研究的重点是用离子液体和聚离子液体官能化的离子烯和纤维素的分子量分析。其他研究包括对生物组织，环境样品和废水的药物残基和其他小分子的分离和分析。它还有助于分析有机光伏的共聚物的分子量分布。该奖项反映了NSF的法定任务，并使用基金会的知识分子优点和更广泛的影响审查标准，被认为值得通过评估来获得支持。