SBIR Phase I: Endoscopic Patient Mask to Limit Aerosolization During Endoscopic Procedures During COVID-19 Pandemic

SBIR 第一阶段：在 COVID-19 大流行期间限制内窥镜手术期间气溶胶的内窥镜患者面罩

• 批准号: 2030942
• 负责人: Azadeh Khanicheh
• 金额: $ 25.6万
• 依托单位: ENVISION ENDOSCOPY, INC.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2030942&HistoricalAwards=false
• 关键词: SBIR; Phase; Endoscopic; Patient; Mask

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to help manage COVID-19 transmission in hospitals with a novel patient face mask to limit transmission of SARS-CoV-2 virus during endoscopic procedures. All endoscopic procedures are considered aerosol-generating procedures because of the possibility of coughing and retching during upper endoscopy, and the passage of flatus during colonoscopy. The proposed patient endoscopic mask limit the spread of microdroplet and aerosols from the patient. This project proposes to develop an endoscopy mask which will be disposable, single use, with an oral opening for the introduction of an endoscope to the gastrointestinal tract. The proposed solution will allow most type of endoscopes, probes, and tubes to be inserted through the mask and enter the mouth or nose, while providing a seal between the mask and scope to limit leakage during the procedure. In addition, it will reduce the post-procedure wait time needed for air circulation in the endoscopy room to remove aerosols for the safety of patients and gastrointestinal health care givers. The solution will be useful for managing transmissions of any airborne infections. This Small Business Innovation Research (SBIR) Phase I project will develop a novel technology that seals between the mask opening and an endoscope, while allowing the endoscope's advancement inside the gastrointestinal tract. The challenge with sealing the mask comes from the scope, which must have significant freedom of motion when it is inserted into the mouth of a patient. The proposed mask will have an access for suction to clear airway secretions and to remove aerosol and micro-droplets generated during endoscopic procedures. If successful, this seal technology can be utilized in other aerosol-generating clinical applications, such as reducing spread of aerosolized droplets of blood in laparoscopic surgery procedure.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项小型企业创新研究（SBIR）I期项目的更广泛的影响/商业潜力是帮助管理带有新型患者口罩的医院的Covid-19传播，以限制内窥镜检查过程中SARS-COV-2病毒的传播。 所有内窥镜手术都被认为是气溶胶生成程序，因为内窥镜检查过程中可能咳嗽和屈服，以及在结肠镜检查过程中通过Fltus的通过。提出的患者内窥镜面膜限制了微螺旋体和气溶胶的扩散。该项目提议开发一个内窥镜掩模，该面膜将是一次性的，单一的用途，并进行口服开口，用于向胃肠道引入内窥镜。所提出的解决方案将允许大多数类型的内窥镜，探针和管子通过面具插入并进入口腔或鼻子，同时在口罩和范围之间提供密封件，以限制手术过程中的泄漏。此外，它将减少内窥镜检查室中空气循环所需的后等待时间，以清除气雾剂，以确保患者和胃肠道医疗保健给予者的安全。该解决方案将有助于管理任何空气传播感染的传播。 这项小型企业创新研究（SBIR）I阶段项目将开发一项新型技术，可以在面具开口和内窥镜之间密封，同时允许内窥镜在胃肠道内部进步。密封面具的挑战来自范围，当将其插入患者口中时，它必须具有显着的运动自由。拟议的面膜将有吸力访问清除气道分泌物，并去除内窥镜手术过程中产生的气溶胶和微滴。如果成功的话，该密封技术可以用于其他气溶胶生成的临床应用中，例如在腹腔镜手术程序中减少血液液滴的传播。该奖项反映了NSF的法定任务，并被认为是通过该基金会的知识分子功能和广泛的影响来评估CRITERIA的评估，认为这是值得通过评估的支持。