MRI: Acquisition of A 90 MHz NMR Spectrometer: Initiating a Bioinspired Undergraduate Student Achievers in Research (USTAR) Program in a Two-Year College

MRI：购买 90 MHz NMR 波谱仪：在两年制大学中启动仿生本科生研究成就 (USTAR) 计划

• 批准号: 1920137
• 负责人: Joseph Rugutt
• 金额: $ 24.28万
• 依托单位: Missouri State University - West Plains
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1920137&HistoricalAwards=false
• 关键词: MRI; Acquisition; 90; MHz; NMR

This award is supported by the Major Research Instrumentation and the Chemistry Instrumentation Programs. Professor Joseph Rugutt from Missouri State University - West Plains and colleagues are acquiring a 90 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the examination of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the rates of interactions between molecules in solution or in the solid state. The NMR studies improve understanding of synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students that impacts green chemistry and recyclable ionic liquids used to accelerate reaction rates. Many students use the spectrometer in a bioinspired initiative named "Undergraduate STudent Achievers in Research" (USTAR) that promotes student participation in STEM (science technology, engineering and mathematics) at the institution and at neighboring high schools in Missouri.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. This instrument acquisition especially impacts the characterization of synthesized bioassay-directed chalcones which are aromatic ketones that form the central core of important biological compounds. The syntheses incorporate nanomaterials that can be used in green chemistry and molecular modeling and for spectroscopic studies. The researchers are generating a small library of chalcones that are tested against biological targets. They are also studying ionic liquids to be used as catalysts to accelerate chemical reactions.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项得到了主要的研究工具和化学工具计划的支持。密苏里州立大学的约瑟夫·鲁古特教授 - 西平原和同事正在收购90 MHz核磁共振（NMR）光谱仪。通常，NMR光谱是化学家可用于检查分子结构的最强大工具之一。它用于识别未知物质，以表征分子内原子的特定排列，并研究溶液中分子之间或固态中分子之间相互作用的速率。 NMR研究提高了对合成有机/无机化学，材料化学和生物化学的理解。该仪器是教学的组成部分，也是本科生进行的研究，这些研究影响了用于加速反应率的绿色化学和可回收离子液体。许多学生在一项名为“研究中的本科生成就者”（USTAR）的生物启发计划中使用光谱仪，该计划促进了该机构的STEM（科学技术，工程和数学）以及密苏里州的邻近高中的参与。该仪器的获取特别影响了合成生物测定指导的Chalcones的表征，这些酮是芳香酮，构成了重要生物化合物的核心核心。这些合成结合了可用于绿色化学和分子建模以及光谱研究的纳米材料。研究人员正在生成一个针对生物学靶标进行测试的小型筹码库。 他们还在研究用作加速化学反应的催化剂的离子液体。该奖项反映了NSF的法定任务，并认为使用基金会的知识分子优点和更广泛的影响审查标准，认为值得通过评估来获得支持。