MRI: Acquisition of a micro-CT for broad integrative biology use and building resources towards the Imaging Center of the Pacific

MRI：采购微型 CT，用于广泛的综合生物学用途并为太平洋成像中心建设资源

• 批准号: 1828802
• 负责人: Megan Porter
• 金额: $ 33.56万
• 依托单位: University of Hawaii
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-10-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1828802&HistoricalAwards=false
• 关键词: MRI; Acquisition; micro; CT; broad

An award is made to the University of Hawai'i at M&#0257noa to purchase a micro-computed tomography (&#0181CT) instrument. This type of instrument has become an important and widely-used used technology in basic research due to its ability to generate fast, reproducible, non-destructive 3-D imaging of a broad range of tissues. The new &#0181CT system will significantly enhance a broad spectrum of local research programs, enabling researchers to initiate, continue, and expand studies of taxonomy in corals, insects and mollusks; sensory system evolution in arthropods and fish; morphology and physiology in frogs and sea spiders; and the impacts of ocean acidification on corals, among many others. This new imaging instrument will be accessible to life science researchers across campus, as well as graduate and undergraduate students, promoting the training of young scientists in advanced 3D imaging technologies. By partnering with &#0181CT users from both the University of Hawai'i and the Bernice Pauahi Bishop Museum in Honolulu, the PI and co-PI will build a Virtual Museum of 3D models of native Hawaiian biodiversity that will be accessible online to the general public and to researchers around the world. These 3D scans of native fauna will also be used to create large scale, 3D models for biodiversity exhibits at the Bishop Museum. The new &#0181CT imaging system will be added to the University of Hawai'i at M&#0257noa Center of Advanced Bioimaging Research (CABR) to develop a comprehensive, multi-modality research facility that will serve the local Hawaiian, and broader Pacific, research community. The location of the instrument affords researchers access to fast, affordable, easy-to-use, non-invasive imaging techniques in one of the premier hotspots of island biodiversity, allowing for studies of the unique, endemic, and rapidly declining fauna found in Hawai'i. The new instrument will support 3D microscopy of hard and soft tissue imaging, capable of mapping genome-phenome interactions, physiology, metabolism, and molecular interactions in living animals, and enhancing efforts to conduct place-based research. The new instrumentation builds on the initial strong investment by UH administration in imaging technology and will support interdisciplinary research, education, and training. The multimodality capability created by the addition of a &#0181CT imaging system to the University of Hawai'i imaging resources will make it unique among bioimaging facilities across the nation because of the access afforded to researchers and students engaged in basic science.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

夏威夷大学 M&#0257noa 获得了购买微型计算机断层扫描 (&#0181CT) 仪器的奖励。 由于这种类型的仪器能够对多种组织产生快速、可重复、非破坏性的 3D 成像，因此它已成为基础研究中重要且广泛使用的技术。新的 CT 系统将显着增强广泛的当地研究计划，使研究人员能够启动、继续和扩大珊瑚、昆虫和软体动物的分类学研究；节肢动物和鱼类的感觉系统进化；青蛙和海蜘蛛的形态和生理学；以及海洋酸化对珊瑚的影响等。整个校园的生命科学研究人员以及研究生和本科生都可以使用这种新型成像仪器，从而促进对先进 3D 成像技术的年轻科学家的培训。 通过与夏威夷大学和檀香山 Bernice Pauahi Bishop 博物馆的 CT 用户合作，PI 和联合 PI 将建立一个夏威夷本土生物多样性 3D 模型虚拟博物馆，公众可以在线访问该博物馆公众和世界各地的研究人员。 这些本地动物群的 3D 扫描还将用于为毕夏普博物馆的生物多样性展览创建大型 3D 模型。新的 CT 成像系统将被添加到夏威夷大学 M&#0257noa 高级生物成像研究中心 (CABR)，以开发一个综合性、多模态研究设施，为夏威夷当地和更广泛的太平洋地区、研究社区。该仪器的位置使研究人员能够在岛屿生物多样性的主要热点之一获得快速、负担得起、易于使用的非侵入性成像技术，从而能够研究夏威夷发现的独特、特有和迅速减少的动物群'我。新仪器将支持硬组织和软组织成像的 3D 显微镜，能够绘制活体动物的基因组-表型相互作用、生理学、新陈代谢和分子相互作用，并加强开展基于地点的研究。新仪器建立在夏威夷大学管理部门最初对成像技术的大力投资的基础上，并将支持跨学科研究、教育和培训。 通过在夏威夷大学成像资源中添加 CT 成像系统所创建的多模态能力，将使其在全国生物成像设施中独一无二，因为为从事基础科学的研究人员和学生提供了访问权限。该奖项反映了通过使用基金会的智力价值和更广泛的影响审查标准进行评估，NSF 的法定使命被认为值得支持。