MRI: Launching an undergraduate-driven Genomics Center through acquisition of an Illumina MiSeq

MRI：通过收购 Illumina MiSeq 启动本科生驱动的基因组学中心

• 批准号: 1828738
• 负责人: John McCormack
• 金额: $ 22.66万
• 依托单位: Occidental College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-10-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1828738&HistoricalAwards=false
• 关键词: MRI; Launching; undergraduate; driven; Genomics

An Award is made to Occidental College to support the acquisition of a next-generation DNA sequencing system. The Moore Laboratory of Zoology and BioScience building at Occidental College will feature a new Genomics Center and Ancient DNA Lab, which will act as a collaborative hub for faculty and student research in Biology. The new sequencer will enable faculty and undergraduate research in collections-based and marine genomic research that involves specimen of birds, marine invertebrates, fish, amphibians, and a range of other species. Faculty users of the sequencer system will lead semester-long courses to generate data and explore questions in their discipline. Additionally, the sequencer system will enhance a successful and established NSF S-STEM program called COSMOS (Creating Opportunities in Science and Mathematics for Occidental Students), which targets freshman from backgrounds under-represented in STEM.The new sequencer system will be used to advance research in the environmental sciences with particular focus on environmental change through time and urban biodiversity. Specifically, results will elucidate change in North American birds by using the Mexican bird collection at the Moore Laboratory of Zoology, including 49,000 specimens collected at 300 sites across Mexico when habitats were largely intact (1933-1955). The sequencer will also help to advance research on species diversity and evolution of mollusks with the Cosman Shell Collection (110,000 specimens with strengths in Hawaii and the Pacific), as well as evolutionary and ecological questions involving the fish collection of the Vantuna Research Group (15,000 specimens and one of the best collections of the Southern California Bight). Other faculty research enabled by the sequencer includes urban biodiversity genomics on Los Angeles salamanders, parrots, and near-shore rocky-reef fishes, as well as research on Pacific deep-sea symbioses and the evolution of cone snail venom. The results of these studies will be published in peer-reviewed journals, presented at scientific meetings, and used in public outreach activities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

向西方学院颁发了奖励，以支持收购下一代DNA测序系统。西方学院动物学和生物科学大楼的摩尔实验室将设有一个新的基因组中心和古老的DNA实验室，该实验室将充当生物学教师和学生研究的合作枢纽。新的音序器将在基于收集的和海洋基因组研究中实现教师和本科研究，其中涉及鸟类，海洋无脊椎动物，鱼类，两栖动物和许多其他物种的标本。 Sequencer系统的教师用户将领导学期的课程，以生成数据并在其学科中探索问题。此外，Sequencer系统将增强一个名为Cosmos的成功且已建立的NSF S-STEM计划（为西方学生创造了科学和数学的机会），该计划的目标是从STEM中代表性不足的背景中的新生。新的Sequencer System将使用新的Sequencer System来推进对环境科学的促进对环境的研究，以通过时间和尿布生物为目标。具体而言，结果将通过在摩尔动物学实验室使用墨西哥鸟类收藏品阐明北美鸟类的变化，其中包括在栖息地很大程度上完好无损时在墨西哥300个地点收集的49,000个标本（1933-1955）。该测序仪还将通过Cosman Shell Collection（在夏威夷和太平洋地区具有优势的110,000个标本），以及涉及Vantuna Research Group的鱼类（15,000个标本和南加州最佳集合之一）的进化和生态问题来帮助推进对软体动物的物种多样性和演变的研究。该测序师启用的其他教师研究包括有关洛杉矶sal，鹦鹉和近岸岩石冰冻鱼类的城市生物多样性基因组学，以及对太平洋深海共生的研究以及锥蜗牛毒液的演变。 这些研究的结果将在经过同行评审的期刊上发表，在科学会议上提出，并在公共宣传活动中使用。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的智力优点评估来支持的，并具有更广泛的影响。