MRI: Acquisition of a Tabletop High-Resolution Scanning Electron Microscope

MRI：购买台式高分辨率扫描电子显微镜

• 批准号: 1828038
• 负责人: Daniele Musumeci
• 金额: $ 17万
• 依托单位: CUNY York College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-10-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1828038&HistoricalAwards=false
• 关键词: MRI; Acquisition; Tabletop; Resolution; Scanning

Non-Technical DescriptionThis Major Research Instrumentation project supports the acquisition of a tabletop high-resolution scanning electron microscope at York College of the City University of New York (York College/CUNY). The acquired scanning electron microscope is used in a wide range of fields including chemistry, geology, environmental science, and pharmaceutical science; it enables the training of undergraduate and master's students in the fundamental principles of scanning electron microscopy, and enhances the curriculum activities for pre-service teachers by providing them with advanced skills and curriculum content. The tabletop scanning electron microscope is also part of a substantial growth plan for a new Master's program at York College and a key instrument for expanding and improving research and training activities that are highly beneficial for York College students in the science disciplines. Technical DescriptionThe tabletop high-resolution scanning electron microscope enables compositional and topographical analysis of metals, nanoparticles, pharmaceutical materials, and biomaterials. It is used in multidisciplinary research projects such as 1) elucidation of the crystallization processes of materials, 2) investigation of metal contamination in aquifers, 3) elucidation of molecular mechanisms of amyloid formation from mutant peptides, and 4) study of the anti-inflammatory and pro-inflammatory effects of nanoparticles in their interactions with biological systems. The instrument can perform at a 1-30 kV accelerating voltage range; it is equipped with backscatter and secondary electron detectors, an energy dispersive X-ray spectrometer, and a variable aperture that can provide a similar resolution to some full-size systems. The low costs of maintenance, the modest infrastructural requirements, and the excellent ease-of-use make the instrument a convenient and versatile analytical tool for York College faculty members and other researchers, who mostly rely on undergraduate students for their research projects.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

非技术描述该重大研究仪器项目支持在纽约城市大学约克学院（约克学院/纽约市立大学）购买一台台式高分辨率扫描电子显微镜。所获得的扫描电子显微镜应用领域广泛，包括化学、地质学、环境科学、药物科学等；它能够对本科生和硕士生进行扫描电子显微镜基本原理的培训，并通过向他们提供先进的技能和课程内容来增强职前教师的课程活动。台式扫描电子显微镜也是约克学院新硕士课程实质性发展计划的一部分，也是扩大和改进研究和培训活动的关键工具，这对约克学院科学学科的学生非常有益。技术说明台式高分辨率扫描电子显微镜可以对金属、纳米颗粒、药物材料和生物材料进行成分和形貌分析。它用于多学科研究项目，例如 1) 阐明材料的结晶过程，2) 研究含水层中的金属污染，3) 阐明突变肽形成淀粉样蛋白的分子机制，以及 4) 抗炎研究以及纳米颗粒与生物系统相互作用的促炎作用。仪器可在1-30 kV加速电压范围内工作；它配备了反向散射和二次电子探测器、能量色散 X 射线光谱仪和可变孔径，可以为某些全尺寸系统提供类似的分辨率。低廉的维护成本、适度的基础设施要求以及出色的易用性使该仪器成为约克学院教职人员和其他研究人员（他们的研究项目主要依赖本科生）的方便且多功能的分析工具。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。