REU Site: Undergraduate Research Experience in Biomedical Translational Science and Technology Development

REU 网站：生物医学转化科学与技术开发的本科生研究经验

• 批准号: 1757846
• 负责人: Kaiming Ye
• 金额: $ 36.17万
• 依托单位: SUNY at Binghamton
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1757846&HistoricalAwards=false
• 关键词: REU; Site; Undergraduate; Research; Experience

The rapid expansion of biomedical science has resulted in a short supply of biomedical scientists and engineers at all career levels, presenting an immediate need to educate and train more young people in the skills and knowledge required for biomedical science and engineering. To meet this demand, Binghamton University (BU-SUNY) will host a 10-week summer REU program to train 10 undergraduate students per year in translational biomedical science and engineering. The program will offer undergraduates intensive multidisciplinary hands-on research and professional development training in integrated biomedical translational science and technology development. The program is anticipated to develop a leadership pipeline helping students advance in either their graduate studies or career and professional training in these fields. The teaming of biomedical scientists with engineers has led to the development of this novel and unique REU program. The fourteen participating faculty members combined have trained nearly 684 REU students, leading to 80 peer-reviewed research articles co-authored by undergraduates. BU's strong commitment to undergraduate education and research will ensure the success of the proposed REU program. The broad and cohesive research interests of faculty mentors involved in this program allow for designing and implementing a vigorous summer REU program to offer T-shaped professional training opportunities to undergraduates. Efforts will be made to recruit students from underrepresented groups, such as women, minority students and students from undergraduate institutions and community colleges where undergraduate research training is limited. The outcome of the REU program will be disseminated at national conferences and published in peer-reviewed journals.The REU program will provide students with opportunities to learn how engineering principles can be integrated with medical and life sciences to translate biomedical discoveries into bedside technologies for treating many diseases, such as diabetes and cancers. The program will expose students to medical science, biology, biochemistry, pharmaceutical sciences, neuroscience and cognitive science, as well as to tissue engineering, materials sciences, nanofabrications, genome editing, RNA transcriptome analysis, 3D bioprinting, cell manufacturing, and tissue biofabrication. Interactive workshops covering topics related to biomedical engineering and graduate studies and career development training will inform students of the latest developments in the fields of biomedical science and engineering and professional development opportunities in these fields. Social events related to the REU program will allow students to interact with other REU students on campus facilitating peer learning and collegiality. Field trips to industry sites will introduce students to applications of biotechnology development. The combination of research training, workshops, social events, and field trips will provide students with a foundation in biomedical engineering research, which they can apply to enriching their professional development.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

生物医学科学的迅速扩展导致了各个职业生物医学科学家和工程师的供应，这是在所有职业级别上的供应，这是迫切需要教育和培训更多年轻人，以了解生物医学科学和工程所需的技能和知识。为了满足这一需求，宾厄姆顿大学（BU-Suny）将举办一项为期10周的夏季REU计划，每年培训10名本科生，从事转化生物医学和工程学。该计划将为本科生提供综合生物医学转化科学与技术发展的强化多学科动手研究和专业发展培训。预计该计划将开发一条领导力管道，以帮助学生在这些领域的研究生学习或职业和专业培训中进步。生物医学科学家与工程师的组合导致了这项小说和独特的REU计划的发展。 14名参与的教职员工培训了近684名REU学生，导致了由本科生共同撰写的80个同行评审的研究文章。 BU对本科教育和研究的坚定承诺将确保拟议的REU计划的成功。参与该计划的教师导师的广泛而凝聚力的研究兴趣允许设计和实施剧烈的夏季REU计划，以提供T形的专业培训机会为本科生提供。将努力从代表性不足的群体中招募学生，例如妇女，少数族裔学生以及来自本科研究培训的本科机构和社区学院的学生。 REU计划的结果将在国家会议上传播，并在同行评审的期刊上发表。REU计划将为学生提供机会，以了解如何将工程原理与医学和生命科学融合在一起，以将生物医学发现转化为床边技术，以治疗许多疾病，以治疗许多疾病，例如糖尿病和Cancers和Cancers和Cancers。该计划将使学生了解医学，生物学，生物化学，药物科学，神经科学和认知科学，以及组织工程，材料科学，纳米化，基因组编辑，RNA转录组分析，3D Bioprintose，3D Bioprinting，细胞制造，细胞制造和组织生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物生物。交互式研讨会涵盖了与生物医学工程和研究生学习以及职业发展培训有关的主题，将为学生提供这些领域的生物医学科学和工程以及专业发展机会领域的最新发展。与REU计划相关的社交活动将使学生能够与校园中的其他REU学生互动，从而促进同行学习和合作。到行业网站的实地考察将向学生介绍生物技术开发的应用。研究培训，研讨会，社交活动和实地考察的结合将为学生提供生物医学工程研究的基础，他们可以将其应用于丰富其专业发展。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子优点和更广泛的审查标准来通过评估来支持的。

项目成果

Inducing Tumor Suppressive Microenvironments through Genome Edited CD47−/− Syngeneic Cell Vaccination

• DOI: 10.1038/s41598-019-56370-6
• 发表时间: 2019-12
• 期刊: Scientific Reports
• 影响因子: 4.6
• 作者: Subhadra Jayaraman Rukmini;Huanjing Bi;Puloma Sen;B. Everhart;Sha Jin;K. Ye