I-Corps: Sustainable manufacturing of natural vanillin

I-Corps：天然香兰素的可持续生产

• 批准号: 1640315
• 负责人: Mahdi Abu-Omar
• 金额: $ 5万
• 依托单位: Purdue University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-01 至 2016-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1640315&HistoricalAwards=false
• 关键词: Corps; Sustainable; manufacturing; natural; vanillin; Corps; Sustainable; manufacturing; natural; vanillin

Production of high value chemicals from biomass is an area of increasing interest, especially in the Flavor and Fragrance industry where there is a growing demand for natural and sustainable products. This I-Corps team has developed processes to produce natural ferulate from non-food biomass. Natural ferulate is important to the Flavor and Fragrance Industry as it is used to produce the highly desired natural vanilla. Vanilla is one of the most important products sold in the Flavor and Fragrance Industry. The global flavor and fragrance chemicals market is a $20 billion industry with continuing annual growth rate of 4.3%. At the present time, vanilla represents around $1 billion of this global market with a 13,000 metric ton production volume. Naturally derived vanilla is an important segment of the market and constitutes 2,400 metric tons of this volume. Successful commercialization of this technology would provide a route for domestic production of renewable and sustainable natural vanillin from non-food biomass sources.This team has developed proprietary technologies for selective upgrading of wood lignin to high value chemicals used in the flavor and fragrance industries. A new application of this technology seeks to produce natural ferulate from biomass, while simultaneously working to better understand the customer needs through the I-Corps discovery process. The goal of the discovery process is to validate the hypothesis that natural ferulate produced from non-food biomass will be a valuable product desired by producers of natural vanillin. The scope of the project includes over 100 interviews with relevant industry contacts to test the hypothesis. Methods employed will focus on interviews with members of the entire value chain including; biomass suppliers, producers of ferulate and vanillin, flavor and fragrance compounders and formulators, and distributors. This discovery work will provide essential data and understanding as the project advances in the prototype stage. Prototype scale-up will be conducted through a combination of already constructed in-house reactors, and will also utilize toll manufacturing. Data from the prototype scale-up will be used in combination with the data generated through I-Corps interviews to provide great insight into the commercial viability of the proposed process and recommendations for further scaling.

生物质产生高价值化学物质是一个越来越兴趣的领域，尤其是在对天然和可持续产品需求不断增长的风味和香料行业中。这个I-Corps团队已经开发了从非食品生物量产生天然捕捞的过程。天然气管对风味和香料行业很重要，因为它用于生产高度期望的天然香草。香草是风味和香水行业中最重要的产品之一。全球风味和香水化学品市场是一个耗资200亿美元的行业，持续的年增长率为4.3％。 目前，香草代表着大约10亿美元的全球市场，其产量为13,000公吨。自然衍生的香草是市场的重要部分，构成了2400吨这一卷。该技术的成功商业化将为非食品生物量来源的国内生产可再生和可持续的天然香草素提供一条途径。该团队开发了专有技术，以选择性地升级木木质素为风味和香料工业中使用的高价值化学物质。这项技术的新应用旨在从生物质中产生天然的侵害，同时通过I-Corps发现过程更好地了解客户需求。发现过程的目的是验证以下假设：非食品生物量产生的天然捕捞将是天然香草蛋白生产商所希望的有价值的产品。该项目的范围包括与相关行业联系人进行100多次访谈，以检验该假设。采用的方法将重点介绍与整个价值链成员的访谈，包括：生物量供应商，禁忌和香草蛋白的生产商，风味和香料化合物和配方剂以及分销商。随着项目在原型阶段的发展，这项发现工作将提供基本的数据和理解。原型扩展将通过已经构建的内部反应堆组合进行，并将利用收费制造。来自原型扩展的数据将与通过I-Corps访谈生成的数据结合使用，以深入了解所提出过程的商业可行性和进一步缩放的建议。