EAGER: Novel techniques for the selective collection and separation of highly-oxidized organic compounds through the application of CO2-triggered "switchable" polarity surfaces

EAGER：通过应用二氧化碳触发的“可切换”极性表面选择性收集和分离高度氧化的有机化合物的新技术

• 批准号: 1622389
• 负责人: Drew Gentner
• 金额: $ 10万
• 依托单位: Yale University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-15 至 2018-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1622389&HistoricalAwards=false
• 关键词: EAGER; Novel; techniques; selective; collection

1622389Gentner, DrewThis proposal addresses an important aspect of the chemistry of air pollutants. The research will develop novel tools and methods that overcome present analytical barriers. The principal investigator (PI) will develop new technologies to address future problems related to the environment or other challenges relevant to society. This proposal has clear broad impacts on society and well-being via addressing the environmental health risk of air pollution.The primary objective of this proposal is to demonstrate the efficacy of "switchable" polarity materials for the collection and/or chromatographic separation of the most elusive components of the atmosphere that have high polarity and hydrophilicity due to their highly oxidized state. The PI will explore and evaluate methods that use switchable surfaces to alter the polarity of sample collection media and/or sample analysis with changes in the stationary phase of gas or liquid chromatography systems. The polarity of switchable materials is increased via reversible reactions with added carbon dioxide (CO2). Subsequent purging with an inert gas or solvent removes the CO2 and returns the material to its low-polarity precursor. This provides a novel and potentially transformative way to selectively collect/separate polar chemical species that are thermally-degraded or lost in other analytical instrumentation. The techniques proposed would seed a new generation of chromatography methods (with Liquid and Gas Chromatography) where the polarity of the stationary phase can be changed rather than the mobile phase, opening new avenues of analysis and potentially reducing solvent needs. There are many applications to gas- and aerosol-phase compounds relevant to the atmosphere, but also to other laboratory methods where polar analytes require collection/separation from a fluid or chromatographic separation without solvents. This includes novel air sampling inlets of minimal size with coupled collection and separation of polar compounds on the same device. There is also the potential for sampling systems that are directly applicable to the study of water-soluble compounds and their aqueous chemistry in the atmosphere. The results of these methods will seed a new understanding of atmospheric oxidation chemistry that will improve models and enable comprehensive air quality management plans. The anticipated results will aid in sustainability science by providing new usable knowledge to model future air quality, formulate policy, and inform the public. The proposal also contributes to training and career development for a postdoctoral scholar. The results will be quickly disseminated to the public via a potential high-impact journal publication and publically available papers and information on the group website.

1622389Gentner，Drewthis提案介绍了空气污染物化学的重要方面。该研究将开发出克服当前分析障碍的新颖工具和方法。首席研究员（PI）将开发新技术，以解决与环境或与社会有关的其他挑战有关的未来问题。该提案通过解决空气污染的环境健康风险对社会和福祉产生了明显的影响。该提案的主要目的是证明“可切换”极性材料在收集和/或色谱分离大气中具有高极性和由于其高度氧化状态而具有很高极性和水的功效。 PI将探索和评估使用可切换表面的方法，以改变样品收集介质和/或样品分析的极性，并随着气体或液相色谱系统的固定阶段的变化而变化。可切换材料的极性通过与添加的二氧化碳（CO2）的可逆反应提高。随后用惰性气或溶剂清除将二氧化碳去除，并将材料返回其低极性前体。这提供了一种新颖的且潜在的变革方式，可以选择性地收集/独立的极性化学物种，这些化学物种在其他分析仪器中被热衰减或丢失。提出的技术将播种新一代的色谱方法（带有液态和气相色谱法），其中固定相的极性可以更改而不是流动相，开辟了新的分析途径并潜在地减少溶剂需求。与大气相关的气体和气溶胶相化合物有许多应用，也有与其他实验室方法相关的，极性分析物需要从没有溶剂的流体或色谱分离中收集/分离。这包括最小尺寸的新型空气采样入口，并在同一设备上耦合收集和极性化合物分离。还具有直接适用于研究水溶性化合物及其在大气中水性化学的研究的潜力。这些方法的结果将使人们对大气氧化化学反应有了新的了解，这将改善模型并实现全面的空气质量管理计划。预期的结果将通过提供新的可用知识来建模未来的空气质量，制定政策并告知公众，从而有助于可持续性科学。该提案还为博士后学者的培训和职业发展做出了贡献。该结果将通过潜在的高影响力期刊出版物以及公开可用的论文和信息在集团网站上的公开信息迅速传播给公众。