I-Corps: Three-Demensional Printing of a Customizable Accommodating Intraocular Lens

I-Corps：可定制可调节人工晶状体的三维打印

• 批准号: 1519687
• 负责人: Cheng Sun
• 金额: $ 5万
• 依托单位: Northwestern University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-12-15 至 2016-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1519687&HistoricalAwards=false
• 关键词: Corps; Three; Demensional; Printing; Customizable

Cataract surgery is the most common surgery in the US, with an estimated 3 million per annum. The surgery involves the removal of the cloudy intraocular lens (IOL) due to a cataract growth that prevents patients from seeing clearly. While there has been advancement in instruments that remove the lens, there remains a great demand to improve replacement IOLs such that patients no longer require spectacles after surgery. Often times, due to anatomical differences between patients and variability in the patient's reaction to existing IOLs, patients may suffer from presbyopia or difficulty to focus on close objects. Nearly 50% of cataract surgeries result in need for spectacles. This I-Corps team is working to commercialize a personalized intraocular lens manufactured utilizing platform three-dimensional (3D) printing technology. Developed by prominent Northwestern University engineering faculty, this patent pending technology can allow ophthalmologists to individually tailor for each patient a replacement lens that has been designed to bio-mimic the natural lens. This significant improvement has the potential to yield fewer surgical complications and eliminate the need for glasses after cataract surgery, improving patient satisfaction and quality of life.

白内障手术是美国最常见的手术，每年估计有 300 万例。该手术涉及摘除浑浊的人工晶状体（IOL），因为白内障生长导致患者看不清东西。尽管摘除晶状体的器械已经取得了进步，但仍然迫切需要改进替换人工晶状体，以便患者在手术后不再需要眼镜。很多时候，由于患者之间的解剖学差异以及患者对现有人工晶状体的反应的差异，患者可能患有老花眼或难以聚焦于近距离物体。近 50% 的白内障手术需要佩戴眼镜。 I-Corps 团队正致力于将利用平台三维 (3D) 打印技术制造的个性化人工晶状体商业化。这项正在申请专利的技术由著名的西北大学工程学院开发，可以让眼科医生为每位患者单独定制替换晶状体，该晶状体的设计目的是仿生自然晶状体。这一重大改进有可能减少手术并发症，并消除白内障手术后佩戴眼镜的需要，从而提高患者满意度和生活质量。