Collaborative Research: Understanding Machining-Induced Influences to Ultra-Fine Grained Pure Titanium for Biomedical Applications

合作研究：了解机械加工对生物医学应用超细晶纯钛的影响

• 批准号: 1404926
• 负责人: Yong Huang
• 金额: $ 14万
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1404926&HistoricalAwards=false
• 关键词: Collaborative; Research; Understanding; Machining; Induced

This collaborative research award supports fundamental research on machining of ultra-fine grained pure titanium for biomedical applications. The research will test the hypothesis that machining induces microstructure changes in severe plastic deformation-processed ultra-fine grained metals, which affects their functionality and cell-material interaction performance. Specifically, key research activities include fabricating bulk ultra-fine grained titanium using equal channel angular extrusion, characterizing the machining-induced microstructure change and functionality variation in terms of grain size, dislocation density, residual stress, and corrosion behavior, and investigating machining-induced cell-material interaction alterations in terms of osteoblast cell adhesion and proliferation. Ultra-fine grained titanium bars will be studied because of titanium's promising use for medical implants and prosthetics.Research results will provide knowledge and understanding of machining-induced material property variations and functionality alterations of severe plastic deformation-processed bulk ultra-fine grained titanium. The methodology will contribute to the adoption of ultra-fine grained metals in the healthcare industry requiring high strength and corrosion resistance and the automobile industry requiring high strength-to-weight ratios. This collaborative research project features a unique collaboration among materials processing, machining, and biomedical manufacturing researchers. The research activities will promote advanced manufacturing for healthcare applications as well as disciplinary education in materials, materials processing, and manufacturing through curriculum development. The research will also positively impact the participation of diverse groups and promotion of Science, Technology, Engineering, and Mathematics activities at the University of Florida, Texas A&M, and Georgia Tech.

该合作研究奖支持用于生物医学应用的超细晶粒纯钛加工的基础研究。该研究将检验这样的假设：加工会引起严重塑性变形加工的超细晶粒金属的微观结构变化，从而影响其功能和细胞-材料相互作用性能。具体来说，关键研究活动包括使用等通道角挤压制造大块超细晶钛，表征加工引起的微观结构变化和晶粒尺寸、位错密度、残余应力和腐蚀行为方面的功能变化，并研究加工引起的微观结构变化和功能变化。成骨细胞粘附和增殖方面的细胞-材料相互作用的改变。由于钛在医疗植入物和假肢方面的应用前景广阔，因此将研究超细晶粒钛棒。研究结果将为加工引起的材料性能变化和经过严重塑性变形加工的大块超细晶粒钛的功能改变提供知识和理解。该方法将有助于在需要高强度和耐腐蚀性的医疗保健行业以及需要高强度重量比的汽车行业中采用超细晶粒金属。该合作研究项目以材料加工、机械加工和生物医学制造研究人员之间的独特合作为特色。研究活动将通过课程开发促进医疗保健应用的先进制造以及材料、材料加工和制造方面的学科教育。该研究还将对不同群体的参与以及佛罗里达大学、德克萨斯农工大学和佐治亚理工学院的科学、技术、工程和数学活动的推广产生积极影响。