Unveiling the diversity and ecological role of the obligate parasitic fungi in phylum Cryptomycota

揭示隐菌门专性寄生真菌的多样性和生态作用

基本信息

批准号：
1354625
负责人：
Timothy James
金额：
$ 55万
依托单位：
Regents of the University of Michigan - Ann Arbor
依托单位国家：
美国
项目类别：
Continuing Grant
财政年份：
2014
资助国家：
美国
起止时间：
2014-03-01 至 2018-02-28
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1354625&HistoricalAwards=false
关键词：
Unveiling diversity ecological role obligate

项目摘要

This project will investigate the biological and genetic diversity of a recently discovered group of fungi known as Cryptomycota. The group is primarily known only from molecular signatures which have been ubiquitously recovered in the environment using DNA techniques. From what little is known of the group, these fungi appear to be parasitic on other organisms, yet, the precise set of hosts and habitat requirements of Cryptomycota remain mysterious. This research will catalog the diversity of the group and provide novel insights into its morphology, host-range, and environmental function. Individual cells isolated from multiple habitat types in North America will be will be analyzed using state-of-the-art genomics methods and microscopy to put a face and function onto organisms that heretofore have been merely characterized as environmental barcodes.Cryptomycota apparently make up a large proportion of the diversity of organisms in many habitats, ranging from ponds and soil to the sea. Understanding the function of these organisms and what they parasitize is vital for developing a predictive understanding of food webs and nutrient cycling. Moreover, elucidating what organisms these fungi parasitize could have significant implications for the security of our food supply and the production of biofuels. There may also be implications for human health. The senior personnel will train postdoctoral researchers, graduate and undergraduate students in modern techniques of mycology, genomics, and bioinformatics. The DNA sequence data generated in this study will be made publicly available through webservers, which will be enriched with educational and research content regarding Cryptomycota.

该项目将研究最近发现的一组被称为隐霉菌的真菌的生物学和遗传多样性。该组主要仅从使用DNA技术在环境中无处不在的分子特征中知道。从对该群体的知之甚少，这些真菌似乎是其他生物的寄生虫，但是，Cryptomycota的确切宿主和栖息地要求仍然很神秘。这项研究将分类小组的多样性，并为其形态，宿主范围和环境功能提供新的见解。将使用最先进的基因组学方法和显微镜对北美多种栖息地类型分离的单个细胞进行分析，以将脸部和功能放在迄今为止被描述为环境条形码的有机体上。Cryptomypomycota显然构成了许多生栖息地的大量生物体，从Peconts和parders rangss rangs and rangs and rangs rangd and range and rangess rangess and rangess rangess rangess and the rangesssive。了解这些生物的功能及其寄生的功能对于对食物网和营养循环的预测理解至关重要。此外，阐明这些真菌寄生的生物是什么可能对我们的粮食供应和生物燃料的生产产生重大影响。可能对人类健康有影响。高级人员将培训现代的真菌学，基因组学和生物信息学技术的博士后研究人员，研究生和本科生。本研究中生成的DNA序列数据将通过WebServer公开获得，Weberver将富含有关密码菌病的教育和研究内容。