NSF Postdoctoral Fellowship in Biology FY 2013

2013 财年 NSF 生物学博士后奖学金

• 批准号: 1308908
• 负责人: Nareg Djabrayan
• 金额: $ 14万
• 依托单位: Djabrayan Nareg J
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1308908&HistoricalAwards=false
• 关键词: NSF; Postdoctoral; Fellowship; Biology; FY

This Postdoctoral Research Fellowship award to Dr. Nareg Djabrayan is supported by both the Directorate for Biological Sciences and the Office of International Science and Engineering at the National Science Foundation. During the 24-month fellowship, Dr. Djabrayan will work on a project titled, "Repopulation and remodeling of larval Drosophila trachea by imaginal tracheal cells" under the sponsorship of Dr. Jordi Casanova at the Institute for Research in Biomedicine in Barcelona, Spain.The main objective of the proposed research is to understand the way cells integrate information about their identity with information received from their environment in order to coordinate their behavior in the context of an organ and the entire organism. The project will use, as a model, the behavior of stem cells that remodel the breathing organs, or trachea, of the fruit fly Drosophila melanogaster during the transition from the larval to adult form. By understanding the mechanisms that determine the identity of these stem cells as well as the timing of their transition from a quiescent state to one of active growth, this project will gain insight into the logic by which cells determine their behavior based on their identity and their environmental conditions.This project will lead to a better understanding of the controls of cell growth. Because the cells to be studied behave as stem cells that remodel and replace the larval organ with an adult organ, any information gained from the study will be useful for understanding how cells, tissues or organs are restored to normal function. As part of this project, Dr. Djabrayan will participate in workshops organized by the host institute that engages teachers from local high schools. He will also work with the Department of Communications and External Relations at the host institute to disseminate the results of the research to a broader audience via press kits and other non-technical publications.This award provides a unique opportunity for a US scientist to collaborate with foreign scientists, and utilize the unique facilities, expertise and experimental conditions available abroad.

Nareg Djabrayan博士的这项博士后研究奖学金得到了国家科学基金会的生物科学和国际科学与工程办公室的支持。在24个月的奖学金期间，Djabrayan博士将在乔迪·卡萨诺瓦（Jordi Casanova）的赞助下进行一个名为“通过想象中的气管细胞对幼虫果蝇对气管对幼体果蝇气管的重生和重塑”的项目。在器官和整个生物体的背景下协调其行为。 该项目将用作模型，在从幼虫到成年形式的过渡期间，将果蝇果蝇果蝇的呼吸器官或气管重塑的干细胞行为。 通过了解确定这些干细胞身份的机制，以及它们从静止状态到活跃生长之一的过渡的时间，该项目将深入了解细胞根据其身份和环境条件确定其行为的逻辑。这将导致对细胞生长的控制更好地理解细胞生长的控制。由于要研究的细胞作为干细胞重塑并用成人器官代替幼虫器官的干细胞，因此从研究中获得的任何信息将有助于了解细胞，组织或器官如何恢复正常功能。作为该项目的一部分，Djabrayan博士将参加由接待当地高中老师组织的主办学院组织的研讨会。他还将与主持人学院的通信和外部关系部合作，通过新闻套件和其他非技术出版物将研究结果传播给更广泛的受众。该奖项为美国科学家与外国科学家合作提供了独特的机会，并利用了独特的设施，专业的，专业的和实验条件。