CAREER: Sustainable and Eco-Friendly Biobased/Biodegradable Polymers

职业：可持续且环保的生物基/可生物降解聚合物

• 批准号: 1032186
• 负责人: Shaoqin 'Sarah' Gong
• 金额: $ 38.68万
• 依托单位: University of Wisconsin-Madison
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1032186&HistoricalAwards=false
• 关键词: CAREER; Sustainable; Eco; Friendly; Biobased

This Faculty Early Career Development (CAREER) grant provides funding to (1) advance the fundamental understanding and processing technology for mass-producing, cost-effective, and high-performance biobased plastics components; and (2) to design, synthesize, characterize, and evaluate new types of biodegradable photopolymerizable macromers with desired material properties for scaffold applications in tissue engineering. The first research focus will build a scientific foundation to better understand the unique composition process structure property relationships for biobased plastics that can serve as guidelines to formulate and process cost-effective and high-performance biobased polymer blends, composites, and nanocomposites. The second research focus will lead to a new family of biodegradable photopolymerizable macromers with a broad spectrum of material properties that not only will fill the urgent needs faced by tissue engineering for suitable materials for targeted tissue regeneration, but also provide a means to elucidate the complex relationships between the cell functions and the characteristics of biomaterials and scaffolds. This new family of biomaterials also can be used for drug delivery and wound-healing applications. The proposed research activities will be integrated with various educational efforts. Especially, the plastics program at UW-Milwaukee will be strengthened through new course development, involving both undergraduate and graduate students in research and collaborating with the local plastics industries. Educational opportunities in engineering for women and minorities also will be improved through outreach activities. Broader impact: The first research focus will broaden the applications of biobased plastics and help to transform today's oil-based economy to a more sustainable and eco-friendly biobased economy in the 21st century while improving our national security by reducing dependency on foreign oil. The second research focus will help to improve the quality of life for millions of people around the world and reduce the cost for treating debilitating diseases. The educational efforts will lead to a stronger plastics program at UW-Milwaukee that will provide a workforce much needed by the local plastics industries and will motivate more women and minority students for a career in engineering.

该学院早期职业发展 (CAREER) 赠款提供资金用于 (1) 推进大规模生产、经济高效和高性能生物基塑料部件的基本理解和加工技术； (2) 设计、合成、表征和评估新型可生物降解的光聚合大分子单体，其具有组织工程支架应用所需的材料特性。第一个研究重点将建立一个科学基础，以更好地了解生物基塑料独特的成分工艺结构性能关系，这可以作为制定和加工经济高效的高性能生物基聚合物共混物、复合材料和纳米复合材料的指南。第二个研究重点将产生一个新的可生物降解的光聚合大分子单体家族，该大分子单体具有广泛的材料特性，不仅将满足组织工程对用于靶向组织再生的合适材料的迫切需求，而且还提供了一种阐明复杂结构的方法。细胞功能与生物材料和支架特性之间的关系。这种新的生物材料家族还可用于药物输送和伤口愈合应用。拟议的研究活动将与各种教育工作相结合。特别是，威斯康辛大学密尔沃基分校的塑料项目将通过新课程的开发得到加强，让本科生和研究生参与研究并与当地塑料行业合作。女性和少数族裔的工程教育机会也将通过外展活动得到改善。更广泛的影响：第一个研究重点将扩大生物基塑料的应用，并有助于将当今的石油经济转变为 21 世纪更加可持续和环境友好的生物基经济，同时通过减少对外国石油的依赖来提高我们的国家安全。第二个研究重点将有助于改善全世界数百万人的生活质量，并降低治疗衰弱性疾病的成本。这些教育工作将为威斯康星大学密尔沃基分校带来更强大的塑料项目，为当地塑料行业提供急需的劳动力，并激励更多女性和少数族裔学生从事工程职业。