COLLABORATIVE RESEARCH: REVSYS: Phylogenetic and revisionary systematics of a diverse clade of avian schistosomes (Platyhelminthes: Schistosomatidae)

合作研究：REVSYS：鸟类血吸虫不同分支的系统发育和修正系统学（扁形动物：血吸虫科）

• 批准号: 1021427
• 负责人: Sara Brant
• 金额: $ 24.35万
• 依托单位: University of New Mexico
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1021427&HistoricalAwards=false
• 关键词: COLLABORATIVE; RESEARCH; REVSYS; Phylogenetic; revisionary

Schistosomes are blood fluke parasites that are significant pathogens of humans as well as domestic and wild vertebrate hosts. The schistosomes that occur in birds represent over 65% of known schistosome species diversity, yet they remain understudied. Bird schistosomes are also responsible for swimmer's itch in humans. In this project, schistosome diversity will be studied by targeted collecting of under sampled and high diversity areas. Identifications will be done using modern approaches to morphological and genetic characterization. The goal is to develop an evolutionary tree of schistosome species, describe the many new species discovered, and produce a monographic treatment for schistosomes. In addition, the resulting evolutionary tree will be used to study the evolution of traits within this clade, with broad implications for evolution within the family Schistosomatidae. This research will greatly increase our understanding of a globally distributed group of parasites and provide the tools necessary for species identification.The project involves faculty from two EPSCoR states and fosters broad international collaboration in Argentina, France, Kenya, and China. The study will improve and build on a natural history museum collection of parasites that is globally accessible. Finally undergraduates and graduate students will be involved with and trained in all aspects of the project. Information generated by this project will be made available to scientists and the medical community, with outreach through K-12 education, and to the general public.

血吸虫是血液氟寄生虫，它们是人类的重要病原体以及家庭和野生脊椎动物宿主。在鸟类中发生的血吸虫占已知的黑素物种多样性的65％以上，但它们仍在研究中。鸟血吸虫还负责人类游泳者的瘙痒。在这个项目中，将通过针对采样和高度多样性领域的有针对性收集来研究血块的多样性。识别将使用现代的形态和遗传表征进行。目的是开发一棵成虫物种的进化树，描述发现的许多新物种，并为血吸虫产生专着治疗。此外，所得的进化树将用于研究该进化枝内性状的演变，对家族棘齿虫中的进化具有广泛的影响。这项研究将大大提高我们对全球分布的寄生虫群体的理解，并提供物种识别所需的工具。该项目涉及来自两个Epscor国家的教职员工，并促进了在阿根廷，法国，肯尼亚和中国的广泛国际合作。这项研究将改善并建立在全球访问的自然历史博物馆集合的基础上。最终，本科生和研究生将在项目的各个方面参与并接受培训。该项目产生的信息将提供给科学家和医学界，通过K-12教育以及公众的宣传。