Experimental Determination of Chemical Structure in the Undergraduate Curriculum: A Data-Driven Approach

本科课程中化学结构的实验测定：数据驱动的方法

• 批准号: 0942850
• 负责人: Dean Johnston
• 金额: $ 19.94万
• 依托单位: Otterbein College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0942850&HistoricalAwards=false
• 关键词: Experimental; Determination; Chemical; Structure; Undergraduate

Chemistry (12)Experimental structure determination remains beyond the experience of most undergraduate students in spite of the central role X-ray crystallography plays in the understanding of materials and biomolecules. Rapid advances in instrumentation and computing power have created equipment that is both rugged enough to allow operation by the non-expert and powerful enough to collect data in a time scale compatible with a teaching environment. Few models exist for the incorporation of crystallographic data and techniques at all levels of the undergraduate chemistry curriculum. The key goals of this project are to: (1) develop a new model for integration of structural methods into the undergraduate chemistry curriculum, (2) assess student engagement and learning when working with experimental structural data, (3) establish a local PUI user group to broaden the incorporation of X-ray diffraction methods and resources into the undergraduate curriculum, and (4) create interactive web-based materials for teaching crystallographic symmetry.Intellectual Merit: The project is creating a model for integration of structural methods into the undergraduate chemistry curriculum. Assessment is occurring at the local, regional and international level while each component of the project addresses the need for high quality resources for teaching structural methods. Connections with the STaRBURSTT CyberInstrumentation Consortium are being used to build on previous NSF-supported projects for the incorporation of X-ray structural methods into the undergraduate curriculum. The project builds upon the PI's previous NSF-CCLI project NSF-0536710, "Visual-Spatial Learning: Development of an Interactive Web-Based Symmetry Tutorial," and makes use of the expertise of faculty in synthetic inorganic chemistry and lipid biochemistry.Broader Impacts: The project is impacting students and faculty (1) locally through curricular development and implementation, (2) regionally through a PUI user group, (3) nationally through dissemination of the curricular products and their assessment, and (4) internationally through the development of web-based resources for teaching symmetry in crystallography. Faculty and students are being trained in aspects of crystal growth, X-ray data collection, and X-ray data analysis through laboratory exercises, courses, and workshops. The creation of a cyber-enabled shared use facility dedicated to undergraduate education is providing much needed infrastructure for teaching and undergraduate research in the central Ohio area. Finally, the details of the curricular development project and its evaluation will be disseminated through presentations at national meetings and publication in a chemical education journal.

化学 (12) 尽管 X 射线晶体学在材料和生物分子的理解中发挥着核心作用，但实验结构测定仍然超出了大多数本科生的经验。仪器和计算能力的快速进步创造了既足够坚固以允许非专家操作又足够强大以在与教学环境兼容的时间范围内收集数据的设备。在本科化学课程的各个级别中纳入晶体学数据和技术的模型很少。该项目的主要目标是：(1) 开发一种将结构方法整合到本科化学课程中的新模型，(2) 评估学生在处理实验结构数据时的参与度和学习情况，(3) 建立本地 PUI 用户小组扩大 X 射线衍射方法和资源纳入本科课程的范围，以及 (4) 创建用于晶体学对称性教学的交互式网络材料。智力优点：该项目正在创建将结构方法融入本科课程的模型化学课程。评估在地方、区域和国际层面进行，而该项目的每个组成部分都满足了教学结构方法对高质量资源的需求。与 STaRBURSTT Cyber​​Instrumentation Consortium 的联系被用来建立之前 NSF 支持的项目，将 X 射线结构方法纳入本科课程。该项目以 PI 之前的 NSF-CCLI 项目 NSF-0536710“视觉空间学习：基于网络的交互式对称教程的开发”为基础，并利用了合成无机化学和脂质生物化学方面教师的专业知识。 更广泛的影响：该项目正在 (1) 通过课程开发和实施在当地影响学生和教师，(2) 通过 PUI 用户组在地区影响，(3) 通过课程产品的传播在全国影响及其评估，以及（4）在国际上通过开发基于网络的资源来教授晶体学的对称性。教师和学生正在通过实验室练习、课程和研讨会接受晶体生长、X 射线数据收集和 X 射线数据分析方面的培训。专门用于本科教育的网络共享使用设施的创建为俄亥俄州中部地区的教学和本科生研究提供了急需的基础设施。最后，课程开发项目及其评估的详细信息将通过在全国会议上的演讲和在化学教育期刊上发表来传播。