Viral Paradigms: Molecules, Populations, Ecosystems and Infectious Disease

病毒范式：分子、群体、生态系统和传染病

基本信息

批准号：
0808966
负责人：
Joshua Weitz
金额：
$ 1.26万
依托单位：
Georgia Tech Research Corporation
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2008
资助国家：
美国
起止时间：
2008-01-01 至 2009-12-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=0808966&HistoricalAwards=false
关键词：
Viral Paradigms Molecules Populations Ecosystems

项目摘要

This award will help support a workshop at the Georgia Institute of Technology in January 2008 whose objective is to dramatically alter the landscape of quantitative viral modeling. Scientists will discuss and develop new theoretical and computational tools to bridge multiple spatiotemporal scales in the study of viral dynamics from phage to human pathogens. The intersection of disease ecology and evolution is an emerging field of study, one that until now has occurred in mostly seperate realms. Appreciation has been growing that ecological dynamics can be strongly influenced by viral evolution occurring on the same time scale. A better understanding of viral ecology and evolution may lead to better understanding and control of infectious diseases. The specific biological topic areas of interest include: (i) within-host models of viral dynamics; (ii) constraints of viral exploitation; (iii) immunoepidemiology; (iv) viral inferences via (meta)genomics; (v) ecology and evolution of bacteriophages; and (vi) multi-scale perspectives: from models to data. Invited speakers represent leaders in the fields of experimental biology, mathematical biology, computer science, physics, and mathematics-most of whom have a long track record of viral research. Also participating in the workshop will be junior scientists so as to ensure the visibility of new views and to facilitate the training of graduate students and post-doctoral scholars.

该奖项将帮助支持 2008 年 1 月在佐治亚理工学院举办的研讨会，其目标是极大地改变定量病毒模型的前景。科学家们将讨论和开发新的理论和计算工具，以在从噬菌体到人类病原体的病毒动力学研究中连接多个时空尺度。疾病生态学和进化的交叉点是一个新兴的研究领域，迄今为止，这一领域大多发生在不同的领域。人们越来越认识到，生态动态可能受到同一时间尺度上发生的病毒进化的强烈影响。更好地了解病毒生态学和进化可能有助于更好地了解和控制传染病。感兴趣的具体生物学主题领域包括：（i）病毒动力学的宿主内模型； (ii) 病毒利用的限制； (三) 免疫流行病学； (iv) 通过（元）基因组学进行病毒推论； (v) 噬菌体的生态学和进化； (vi) 多尺度视角：从模型到数据。受邀演讲者代表了实验生物学、数学生物学、计算机科学、物理学和数学领域的领导者，其中大多数人拥有长期的病毒研究记录。参加研讨会的还有年轻科学家，以确保新观点的可见性，并促进研究生和博士后学者的培训。