RUI: Experimental and Theoretical Investigation into the Reactions of Atomic Carbon with Organic Substrates

RUI：原子碳与有机底物反应的实验和理论研究

• 批准号: 0719335
• 负责人: Dasan Thamattoor
• 金额: --
• 依托单位: Colby College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0719335&HistoricalAwards=false
• 关键词: RUI; Experimental; Theoretical; Investigation; into

This RUI award to Professor Dasan M. Thamattoor of the Chemistry Department at Colby College in Waterville, ME has as its goal the production of arc generated carbon atoms and the study of their reactions. Interesting divalent carbon intermediates (carbenes) will be generated by reactions with a variety of organic chemical substrates. More specifically, these organic substrates include alkenes, alkynes, azulene, acid chlorides, 1,2-dicarbonyl compounds and molecules with highly strained single carbon-carbon bonds. The chemistry of these intermediates and the pathways by which they are formed and consumed will be investigated experimentally and by modern computational techniques. The proposed work, which integrates elements of synthetic, mechanistic, and computational organic chemistry, is designed to provide undergraduates with a wholesome research experience, and enable them to make original contributions to scientific knowledge. Among the most important broader impacts of this research, as mentioned above, is the mentoring of undergraduate researchers and training them as future scientists in a predominantly undergraduate institution. A number of ideas for melding research and education, based on approaches that have already met with success, will be implemented. This is exemplified, for instance, by the incorporation of research-like projects and new pedagogical experiments in the introductory organic chemistry laboratory course. The proposal also seeks to continue Prof. Thamattoor's highly successful program that provides research opportunities to high school students over the summer months. Women, minorities, and students from disadvantaged backgrounds will also be recruited to participate in summer research activities. In addition, there will be new initiative that forges partnerships with elementary school teachers to specifically strengthen the science curriculum in the K-3 level. Finally, it is expected that a number of important fundamental chemical reaction pathways will be elucidated.

该 RUI 奖项授予缅因州沃特维尔科尔比学院化学系的 Dasan M. Thamattoor 教授，其目标是电弧生成碳原子的生产及其反应的研究。 有趣的二价碳中间体（卡宾）将通过与各种有机化学底物的反应产生。 更具体地，这些有机底物包括烯烃、炔烃、甘菊环、酰基氯、1,2-二羰基化合物和具有高张力单碳-碳键的分子。这些中间体的化学性质以及它们形成和消耗的途径将通过实验和现代计算技术进行研究。 拟议的工作整合了合成、机械和计算有机化学的元素，旨在为本科生提供有益的研究经验，并使他们能够对科学知识做出原创性贡献。如上所述，这项研究最重要的广泛影响之一是在以本科为主的机构中对本科研究人员进行指导并将他们培训为未来的科学家。 基于已经取得成功的方法，许多融合研究和教育的想法将得到实施。例如，在介绍性有机化学实验室课程中纳入类似研究的项目和新的教学实验就证明了这一点。该提案还旨在继续 Thamattoor 教授非常成功的项目，该项目在夏季为高中生提供研究机会。女性、少数族裔和来自弱势群体的学生也将被招募参加夏季研究活动。此外，还将采取新举措与小学教师建立伙伴关系，专门加强 K-3 级别的科学课程。 最后，预计许多重要的基本化学反应途径将得到阐明。