MRI: Aquisition of a Dip Pen Nanolithography System for Surface Nanofunctionalization

MRI：获取用于表面纳米功能化的浸笔纳米光刻系统

• 批准号: 0619355
• 负责人: Matthew Libera
• 金额: $ 16.79万
• 依托单位: Stevens Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0619355&HistoricalAwards=false
• 关键词: MRI; Aquisition; Dip; Pen; Nanolithography

Technical AbstractThe Stevens Institute of Technology will acquire a dip pen nanolithography (DPN) system. With it, Stevens and its collaborators at area universities will create a novel resource for high-resolution functionalization of surfaces. DPN is a new approach, which is uniquely suited for chemically modifying surfaces at length scales as small as 10 nm. Because of its ability to precisely position its tip, DPN can modulate such chemical modifications in diverse user-defined patterns to enhance a broad range of different research projects. A group of five research-active scientists from three different Northern New Jersey institutions will use the DPN system to substantially enhance a set of forward-looking projects that include: development of nanohydrogel-based protein nanoarrays; coherent surface-enhanced Raman spectroscopy using directed deposition of Ag and Au nanoparticle arrays; and stem cell differentiation on biochemically nanopatterned surfaces. In addition to these research initiatives, the DPN system will also anchor several new educational and outreach activities. For example, new concepts of surface nanofunctionalization will be incorporated into a series of courses offered at Stevens and at the nearby New Jersey Institute of Technology. Forward-looking ideas of nanotechnology will also be introduced into ongoing summer outreach programs to underprivileged high-school students. This effort, executed in collaboration with the American Chemical Society SEED program, will encourage these young people to pursue college opportunities in science and engineering. Lay AbstractDip-pen nanolithography (DPN) is among the newest and most advanced scientific tools for controlling how the surfaces of materials interact with their surroundings. DPN can create patterns that are almost 1000 times smaller than those in state-of-the-art electronic devices like advanced computer chips. Furthermore, DPN can deposit as little as a few molecules at each point in the surface pattern, and this capability gives scientists and engineers impressive new control over chemical reactions that occur at very specific points on a surface. We will use DPN in research projects to learn how individual cells behave when they stick to a surface, to develop new sensors that can detect trace quantities of harmful chemicals, and to build new tools for biomedical research and clinical diagnostics. We will also use the DPN system as a new part of a very successful program called Project SEED that provides summer internships to underpriviledged high-school students. We expect that introducing these students to some of the exciting opportunities associated with nanotechnology will help encourage them to pursue a college education and work towards careers in science and engineering.

技术摘要史蒂文斯理工学院将购买浸笔纳米光刻（DPN）系统。 凭借它，史蒂文斯及其在地区大学的合作者将为表面的高分辨率功能化创建一种新颖的资源。 DPN 是一种新方法，特别适合对小至 10 nm 的长度尺度的表面进行化学修饰。 由于 DPN 能够精确定位其尖端，因此可以以多种用户定义的模式调节此类化学修饰，以增强各种不同的研究项目。 来自新泽西州北部三个不同机构的五名活跃研究科学家组成的小组将使用 DPN 系统来大幅增强一系列前瞻性项目，其中包括：开发基于纳米水凝胶的蛋白质纳米阵列；使用银和金纳米颗粒阵列定向沉积的相干表面增强拉曼光谱；以及干细胞在生化纳米图案表面上的分化。 除了这些研究计划外，DPN 系统还将主持一些新的教育和外展活动。 例如，表面纳米功能化的新概念将被纳入史蒂文斯和附近的新泽西理工学院提供的一系列课程中。 纳米技术的前瞻性理念也将被引入到针对贫困高中生的夏季外展项目中。 这项工作是与美国化学会 SEED 计划合作执行的，将鼓励这些年轻人追求科学和工程方面的大学机会。 摘要浸笔纳米光刻 (DPN) 是控制材料表面与其周围环境相互作用的最新、最先进的科学工具之一。 DPN 可以创建比先进计算机芯片等最先进电子设备中的图案小近 1000 倍的图案。 此外，DPN 可以在表面图案的每个点沉积少量的分子，这种能力为科学家和工程师提供了对表面特定点发生的化学反应的令人印象深刻的新控制。 我们将在研究项目中使用 DPN，了解单个细胞粘附在表面时的行为，开发可以检测痕量有害化学物质的新传感器，并为生物医学研究和临床诊断构建新工具。 我们还将使用 DPN 系统作为名为 Project SEED 的非常成功的计划的新组成部分，该计划为贫困高中生提供暑期实习机会。 我们希望向这些学生介绍一些与纳米技术相关的令人兴奋的机会，将有助于鼓励他们接受大学教育并致力于科学和工程职业。