CAREER: Development of an Integrated Research and Education Program in Nanobiomechanical Analysis of Skeletal Fragility

职业：骨骼脆弱性纳米生物力学分析综合研究和教育项目的开发

• 批准号: 0620061
• 负责人: Ozan Akkus
• 金额: $ 34.48万
• 依托单位: Purdue University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-01-10 至 2012-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0620061&HistoricalAwards=false
• 关键词: CAREER; Development; Integrated; Research; Education

0449188AkkusThis CAREER development project will establish the foundation for integration of research and education at the Department of Bioengineering of the University of Toledo towards developing cures for alleviating skeletal fragility. The proposal seeks to attain the following specific objectives: (1) to understand the molecular and supramolecular level deformation and fracture mechanisms in healthy bone, (2) to determine whether bone's mechanical function can be improved by modulating the size and the geometry of mineral nanocrystals, (3) to integrate this nanobiomechanical perspective with the existing undergraduate- and graduate-level biomechanics curricula, and (4) to realize the participation of undergraduates and high-school students from under-served populations in these research activities.

0449188Akkus这个职业发展项目将为托莱多大学生物工程系的研究和教育一体化奠定基础，以开发减轻骨骼脆弱性的治疗方法。 该提案旨在实现以下具体目标：（1）了解健康骨骼的分子和超分子水平变形和断裂机制，（2）确定是否可以通过调节矿物纳米晶体的尺寸和几何形状来改善骨骼的机械功能，（3）将这种纳米生物力学观点与现有的本科生和研究生生物力学课程相结合，（4）实现来自服务不足人群的本科生和高中生参与这些研究 活动。