GOALI: Characterization of Dense Colloidal Suspensions With Frequency-Domain Photon Migration (FDPM)

GOALI：通过频域光子迁移 (FDPM) 表征致密胶体悬浮液

• 批准号: 0511915
• 负责人: Emile Schweikert
• 金额: --
• 依托单位: Texas A&M Research Foundation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-12-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0511915&HistoricalAwards=false
• 关键词: GOALI; Characterization; Dense; Colloidal; Suspensions

ABSTRACTProposal Number: CTS-0213280Principal Investigator: Sevick-Muraca, Eva MAffiliation: Texas Engineering Exp StaTitle: GOALI - Characterization of Dense Colloidal Suspensions with FDPMIn this project, the PI proposes to (i) develop and test new inverse algorithms for assessing particle size and size distribution in monodisperse, binary, and polydisperse suspensions from experimental multi-wavelength FDPM data, (ii) assess changes in FDPM measured scattering properties arising from depletion force, electrostatic interactions, and colloids functionalized with ligand receptor systems of biological significance; and (iii) evaluate those changes in the context of first principles models of partial structure factor. The final objective of the GOALI project is to develop a low cost, simple diagnostics tool in characterize the interaction between colloidal particles in dense suspensions. Extension of the system to on-line characterization of intermediate and final colloidal products is planned for chemical, pharmaceutical, and biotechnology industries.

摘要提案编号：CTS-0213280 首席研究员：Sevick-Muraca, Eva 隶属关系：德克萨斯工程实验站 标题：GOALI - 使用 FDPM 表征稠密胶体悬浮液 在该项目中，PI 建议 (i) 开发和测试新的反演算法，用于评估颗粒尺寸和来自实验多波长的单分散、二元和多分散悬浮液的粒径分布FDPM 数据，(ii) 评估由消耗力、静电相互作用和具有生物学意义的配体受体系统功能化的胶体引起的 FDPM 测量的散射特性的变化； (iii) 在部分结构因子的第一原理模型的背景下评估这些变化。 GOALI 项目的最终目标是开发一种低成本、简单的诊断工具来表征稠密悬浮液中胶体颗粒之间的相互作用。 计划将该系统扩展到化学、制药和生物技术行业的中间体和最终胶体产品的在线表征。