Conference: Phytochemical Probes/Substrates Network (NSF Workshop Proposal) to be held in Arlington, VA

会议：植物化学探针/底物网络（NSF 研讨会提案）将于弗吉尼亚州阿灵顿举行

• 批准号: 0436054
• 负责人: Ikhlas Khan
• 金额: $ 0.97万
• 依托单位: University of Mississippi
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-01 至 2005-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0436054&HistoricalAwards=false
• 关键词: Conference; Phytochemical; Probes; Substrates; Network

NSF Workshop Proposal Metabolic Biochemistry Program "Phytochemical Probes/Substrates Network" Ikhlas Khan, Ph.D. NCNPR, University of Mississippi Support is requested for a one day workshop for the purpose of drawing key investigators together to discuss the feasibility of bringing the phytochemistry community together to share resources for plant natural product research. For researchers in plant molecular biology, biochemistry, plant physiology, and other fields, the ready availability of phytochemicals that may modulate plant gene/protein expression, or serve as substrates in biochemical pathways of interest, would greatly facilitate progress in the fields and open up new avenues of exploration. It is proposed to create a network of phytochemical researchers which would catalog the availability of such compounds, and where feasible, establish a repository for compound sourcing. The network is anticipated to incorporate the following activities: (1) Creation and maintenance of a web site to serve as an information resource for researchers interested in using phytochemicals as probes/substrates in their research; (2) Generation of a database of investigators and phytochemicals available in their laboratories, catalogued by various structural classes; and (3) Where feasible, the establishment of a corresponding phytochemical repository system to facilitate access to these. To facilitate discussion of this timely and important topic, a one-day workshop will be held to share information and discuss logistics for creating this network. A team of 8-10 scientists from phytochemical disciplines, as well as potential users of such resources, will be assembled to discuss these ideas.Broader Impact: Establishment of a phytochemical substrate/probe network will have high impact on the field of plant biochemistry by increasing availability/accessability of rare compounds to researchers studying plant metabolism, molecular biochemistry, functional genomics, proteomics, metabolomics, pharmacology and pharmacognosy. This is also of importance to researchers at smaller institutions who may not have ready access, economically available sources, or infrastructure to support the isolation/purification/synthesis of needed compounds. The education and training of students and post-doctoral researchers would also be enhanced by the existence of a phytochemical substrate/probe network increasing information and accessability to a diverse bank of compounds.

NSF 研讨会提案代谢生物化学计划“植物化学探针/底物网络”Ikhlas Khan 博士请求密西西比大学 NCNPR 支持举办为期一天的研讨会，目的是将主要研究人员聚集在一起，讨论将植物化学界聚集在一起共享植物天然产物研究资源的可行性。 对于植物分子生物学、生物化学、植物生理学和其他领域的研究人员来说，可以调节植物基因/蛋白质表达或作为感兴趣的生化途径的底物的植物化学物质的现成可用，将极大地促进该领域的进展并开辟新的领域。新的探索途径。建议建立一个植物化学研究人员网络，对此类化合物的可用性进行分类，并在可行的情况下建立一个化合物采购存储库。 该网络预计将包括以下活动： (1) 创建和维护一个网站，为有兴趣在研究中使用植物化学物质作为探针/底物的研究人员提供信息资源； (2) 生成研究人员及其实验室可用的植物化学物质的数据库，按各种结构类别进行编目； (3) 在可行的情况下，建立相应的植物化学物质储存库系统以方便获取这些物质。 为了促进对这一及时而重要的主题的讨论，将举办为期一天的研讨会，以共享信息并讨论创建该网络的后勤工作。 由来自植物化学学科的 8-10 名科学家以及此类资源的潜在用户组成的团队将聚集在一起讨论这些想法。 更广泛的影响：植物化学底物/探针网络的建立将对植物生物化学领域产生重大影响为研究植物代谢、分子生物化学、功能基因组学、蛋白质组学、代谢组学、药理学和生药学的研究人员增加稀有化合物的可用性/可及性。 这对于小型机构的研究人员来说也很重要，他们可能没有现成的途径、经济上可用的资源或基础设施来支持所需化合物的分离/纯化/合成。 植物化学底物/探针网络的存在也将增强学生和博士后研究人员的教育和培训，从而增加信息和获取不同化合物库的可能性。