DISSERTATION RESEARCH: Analysis of the Genetic Architecture of Hybrid Male Sterility in the Drosophila mojavensis Species Group

论文研究：果蝇物种组杂交雄性不育的遗传结构分析

• 批准号: 0414184
• 负责人: Therese Markow
• 金额: $ 1.03万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-15 至 2005-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0414184&HistoricalAwards=false
• 关键词: DISSERTATION; RESEARCH; Analysis; Genetic; Architecture

The nature and number of genetic changes required to form two new species from one ancestral one is a lingering problem in evolutionary biology. A defining feature separate species is their inability to form fertile hybrids. A pair of Drosophila species between which a low number of fertile hybrids still form, have been discovered. By using this pair of species, D. mojavensis and D. arizonae, a combination of molecular and classical genetic techniques can be used to determine how many genetic factors are responsible for the emerging sterility and the chromosomal locations of the factors. Anthropogenic change is fueling the loss of species at an alarming rate. While we have some understanding of the factors that cause loss of species, our understanding of how new species form is sorely lacking. The present study will provide important new information about the origin of new species. At the same time, it will advance our understanding of the genetics of sterility of male insects. Sterile male insect techniques are an important tool in the control of economically important insect pests.

从一个祖先形成两个新物种所需的遗传变化的性质和数量是进化生物学中的挥之不去的问题。一个定义的特征单独的物种是它们无法形成肥沃的杂种。已经发现了一对果蝇之间的一对果蝇，但仍发现了少量的肥沃杂种。通过使用这对莫哈文氏菌和阿里佐尼氏菌，分子和经典遗传技术的组合可以用于确定多少遗传因素负责出现的无菌性和因素的染色体位置。人为变化以惊人的速度助长了物种的损失。尽管我们对导致物种丧失的因素有所了解，但我们对新物种形式的理解非常缺乏。本研究将提供有关新物种起源的重要新信息。同时，它将提高我们对雄性昆虫无菌性遗传学的理解。无菌雄性昆虫技术是控制经济上重要的害虫的重要工具。