US-UK Cooperative Research: Decarboxylation of Carboxymethyl Betaines

美英合作研究：羧甲基甜菜碱的脱羧

• 批准号: 0405210
• 负责人: David Forbes
• 金额: $ 2.38万
• 依托单位: University of South Alabama
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0405210&HistoricalAwards=false
• 关键词: US; UK; Cooperative; Research; Decarboxylation

0405210ForbesThis three-year US-UK cooperative research award supports visits by undergraduate students and the principal investigator to the University of East Anglia. David Forbes of the University of South Alabama and his UK counterpart, Robert Stockman, propose to conduct chemical studies of sulfur ylides and apply their methodologies to medicinally important compounds. Intellectual Merit: Undergraduates at Alabama will participate in several research projects during three-month stays in East Anglia. They will focus on the use of chiral sulfinyl imines as receptors using a methylidene transfer approach and stidy sulfur ylides in model systems. The research project's ultimate goal is to develop a complete synthesis of a system of biological and medicinal importance. Broader Impacts: This international collaboration is highly complementary and combines the expertise of investigators in synthetic organic chemistry and their different synthetic methodologies. It also provides an international research and training experience to undergraduate researchers from a predominantly undergraduate US institution in an EPSCoR state.

0405210 forbesthis三年的US-UK合作研究奖支持本科生和东英吉利大学的主要研究人员的访问。 南阿拉巴马大学和他的英国同行罗伯特·斯托克曼（Robert Stockman）提议对硫ylides进行化学研究，并将其方法应用于具有药物重要的化合物。知识分子的优点：阿拉巴马州的本科生将在东安格利亚（East Anglia）的三个月住宿期间参加几个研究项目。 他们将专注于使用甲基二烯转移方法和模型系统中的甲基硫硫化物的手性磺胺基亚胺作为受体。 研究项目的最终目标是建立对生物学和药物重要性系统的完整综合。更广泛的影响：这种国际合作是高度互补的，并结合了研究人​​员在合成有机化学及其不同合成方法方面的专业知识。 它还为来自EPSCOR州的美国本科学院的本科研究人员提供了国际研究和培训经验。