A New Capillary Sequencer for the Evolutionary Genetics Core Facility at Cornell University

康奈尔大学进化遗传学核心设施的新型毛细管测序仪

基本信息

批准号：
0400433
负责人：
Kelly Zamudio
金额：
$ 12.37万
依托单位：
Cornell University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2004
资助国家：
美国
起止时间：
2004-05-01 至 2006-04-30
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=0400433&HistoricalAwards=false
关键词：
New Capillary Sequencer Evolutionary Genetics

项目摘要

This award provides partial support for purchase of a modern capillary DNA sequencer and supporting computer equipment for the Cornell Evolutionary Genetics Core Facility (EGCF). The instrument will be equipped for both sequence determination and fragment analysis. The facility supports research by evolutionary biologists, population biologists, behavioral ecologists, and systematists. Research in these areas increasingly depends on variation in the DNA sequences of individual organisms to provide information on mating systems, population structure, genealogy, and phylogeny. Automated DNA sequencing and genotyping are critical to studies employing such variation. The facility is used by 19 faculty in seven departments across the Cornell campus, and contributes significantly to their research programs and the educational experience of their graduate and undergraduate students. Their research programs address various aspects of biodiversity, including the origins and maintenance of plant and animal diversity, and the management of taxa of conservation concern or of economic importance. Aside from the impact of each individual user, the facility plays an important role in teaching and training on the Cornell campus. The new equipment will increase throughput and data quality for all users, improve the training of students, and catalyze interactions among evolutionary biologists and ecologists with diverse taxonomic and disciplinary interests.

该奖项为购买现代毛细血管DNA测序仪和康奈尔进化遗传学核心设施（EGCF）的计算机设备提供了部分支持。该仪器将配备序列确定和碎片分析。该设施支持进化生物学家，人群生物学家，行为生态学家和系统主义者的研究。这些领域的研究越来越取决于单个生物体的DNA序列的变化，以提供有关交配系统，种群结构，家谱和系统发育的信息。自动DNA测序和基因分型对于采用这种变异的研究至关重要。该设施在康奈尔大学校园的七个部门的19位教职员工使用，并为他们的研究计划以及研究生和本科生的教育经验做出了重大贡献。他们的研究计划涉及生物多样性的各个方面，包括植物和动物多样性的起源和维护，以及保护群体的管理或经济重要性的管理。除了每个用户的影响外，该设施在康奈尔校园的教学和培训中都起着重要作用。新设备将提高所有用户的吞吐量和数据质量，改善学生的培训，并催化具有多种分类学和学科利益的进化生物学家和生态学家之间的互动。