ATOL: Collaborative Research: The Deep Scaly Project: Resolving Higher Level Squamate Phylogeny Using Genomic and Morphological Approaches

ATOL：合作研究：深鳞项目：使用基因组和形态学方法解决更高级别的鳞状动物系统发育

• 批准号: 0334923
• 负责人: John Wiens
• 金额: --
• 依托单位: SUNY at Stony Brook
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0334923&HistoricalAwards=false
• 关键词: ATOL; Collaborative; Research; Deep; Scaly

A grant has been awarded to Dr. John Wiens of the State University of New York at Stony Brook to study the evolutionary history of squamate reptiles (lizards and snakes). With more than 7,700 species, squamates are the second largest group of vertebrates after birds. Many critical questions in squamate evolution remain unresolved, such as identification of the most primitive lineage of squamates, the origin of snakes, and the relationships of venomous snakes to other snake lineages. An international team of eight investigators from diverse institutions (Brigham Young University, Field Museum of Natural History, San Diego State University, State University of New York-Stony Brook, University of Adelaide, University of Texas-Austin, and Yale University) will collaborate to resolve squamate relationships. Anatomical data from living and fossil forms will be combined with DNA sequences from 50 genes for 142 representative squamate species. Anatomical data will be obtained using traditional methods and new high resolution X-ray scanning techniques. DNA data will be generated by incorporating new tools and databases from recent vertebrate genome projects. Computer modeling will be used to determine how data from molecular and fossil studies can best be combined to reconstruct evolutionary trees. Wiens will help generate sequence data, anatomical data, and the web-site, and will be solely responsible for computer modeling.Squamates are an important model system in biology, and understanding their evolutionary history is critical for a complete picture of vertebrate evolution and ecology. Venomous snakes pose an important threat to human safety in many parts of the world, and identification is critical for effective treatment. An innovative web-site will allow snakebite victims and medical workers to identify the venomous snakes in their area. Postdoctoral researchers and students will be involved in nearly every aspect of the project, and thus the training of many future biologists and educators will be supported.

纽约州立大学斯托尼·布鲁克（Stony Brook）的约翰·维恩斯（John Wiens）授予了一笔赠款，以研究鳞状爬行动物（蜥蜴和蛇）的进化史。 鳞虫拥有7,700多种物种，是仅次于鸟类的第二大脊椎动物。 鳞状进化中的许多关键问题仍未解决，例如识别最原始的鳞状谱系，蛇的起源以及有毒的蛇与其他蛇谱系的关系。 一支由来自不同机构的八名调查人员组成的国际团队（杨百翰大学，野外自然历史博物馆，圣地亚哥州立大学，纽约大学布鲁克大学布鲁克，阿德莱德大学，阿德莱大学，德克萨斯大学奥斯汀大学和耶鲁大学）将合作解决鳞状关系。 来自生物和化石形式的解剖学数据将与142种代表性鳞状物种的50个基因的DNA序列结合使用。 将使用传统方法和新的高分辨率X射线扫描技术获得解剖数据。 DNA数据将通过合并来自最近脊椎动物基因组项目的新工具和数据库来生成。 计算机建模将用于确定如何最好地将来自分子和化石研究的数据结合在一起以重建进化树。 Wiens将有助于生成序列数据，解剖学数据和网站，并将完全负责计算机建模。方形是生物学中的重要模型系统，并且了解其进化历史对于脊椎动物进化和生态学的完整情况至关重要。 有毒蛇在世界许多地方对人类安全构成了重要威胁，并且鉴定对于有效治疗至关重要。创新的网站将使蛇咬的受害者和医务人员能够识别其所在地区的有毒蛇。 博士后研究人员和学生将几乎参与项目的各个方面，因此将支持许多未来的生物学家和教育者的培训。