MRI/RUI: Acquisition of Confocal Microscopy for Life Science Research and Cal State Fullerton

MRI/RUI：为生命科学研究和加州州立大学富勒顿分校购买共焦显微镜

• 批准号: 0321376
• 负责人: Robert Koch
• 金额: $ 39.41万
• 依托单位: CSU Fullerton Auxiliary Services Corporation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0321376&HistoricalAwards=false
• 关键词: MRI; RUI; Acquisition; Confocal; Microscopy

A grant has been awarded to California State University, Fullerton under the direction of Dr. Robert Koch to bring confocal microscopy to the research and research training activities of the life sciences faculty in the Departments of Biological Science and Chemistry & Biochemistry at Cal State Fullerton. This acquisition will bring the fundamental research tool of confocal scanning laser microscopy to the study of cell function by the faculty and students at Cal State Fullerton in keeping with its serious commitment to research and research training. The establishment of the Confocal Microscopy Laboratory will advance the collaborative research of faculty with their students in fields like cell biology with the study of cell signaling and cytoskeletal reorganization in ascidian sperm cells, neurobiology with the study of nicotinic acetylcholine receptor diversity in molluscan neurons, molecular microbiology with the study of mechanisms for bacterial resistance to antibiotics, developmental biology with the study of muscle development in nematodes, biochemistry with the study copper and iron transport in intestine and mammary glands, biology of aging with the study of superoxide dismutase expression in nematodes, comparative physiology with the study of muscle fiber development and endothermy in fishes, and physiological ecology with the study of gut structure in carnivorous and herbivorous fishes. The new research programs made possible by this grant will benefit all students, but, because Cal State Fullerton is a Hispanic serving institution, it will have a particularly important impact on minority student research training programs like Minority Access to Research Careers, Initiative for Minority Student Development, Minority International Research Travel, Bridges-to-the-Doctorate, McNair Scholars, or Undergraduate Mentorship in Environmental Biology where as many as forty minority students per year will have access to the new instrumentation. This grant has the potential to impact more than 600 students per year who go through undergraduate and masters level curricula in the two departments involved. Thus, the establishment of the Confocal Microscopy Laboratory will have a tremendous influence on research and research training activities as well as on the overall educational experience in the life sciences at Cal State Fullerton.

在 Robert Koch 博士的指导下，加州州立大学富勒顿分校获得了一笔拨款，将共聚焦显微镜应用于加州州立大学富勒顿分校生物科学系和化学与生物化学系生命科学系的研究和研究培训活动。 此次收购将把共焦扫描激光显微镜的基础研究工具带入加州州立大学富勒顿分校的教师和学生对细胞功能的研究中，以履行其对研究和研究培训的认真承诺。 共聚焦显微镜实验室的建立将促进教师与学生在细胞生物学（研究海鞘精子细胞中的细胞信号传导和细胞骨架重组）、神经生物学（研究软体动物神经元中的烟碱乙酰胆碱受体多样性）、分子生物学等领域的合作研究。微生物学研究细菌对抗生素的耐药机制，发育生物学研究线虫的肌肉发育，生物化学研究铜和铁在肠道和乳腺中的转运腺体、衰老生物学（研究线虫中超氧化物歧化酶的表达）、比较生理学（研究鱼类的肌纤维发育和吸热）、生理生态学（研究肉食性和草食性鱼类的肠道结构）。这笔赠款带来的新研究项目将使所有学生受益，但是，由于加州州立大学富勒顿分校是一所西班牙裔服务机构，它将对少数族裔学生研究培训项目产生特别重要的影响，例如少数族裔进入研究职业、少数族裔学生倡议发展、少数族裔国际研究旅行、通往博士学位的桥梁、麦克奈尔学者或环境生物学本科生导师计划，每年有多达四十名少数族裔学生将有机会使用新仪器。 这笔赠款每年有可能影响 600 多名在相关两个院系完成本科和硕士课程的学生。 因此，共聚焦显微镜实验室的建立将对加州州立大学富勒顿分校的研究和研究培训活动以及生命科学的整体教育体验产生巨大影响。