Acquisition of a Lifetime Spectrofluorometer

购买终身可用的分光荧光计

• 批准号: 0234537
• 负责人: David McFadden
• 金额: $ 11万
• 依托单位: Boston College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-03-01 至 2006-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0234537&HistoricalAwards=false
• 关键词: Acquisition; Lifetime; Spectrofluorometer

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Boston College will acquire a Spectrofluorometer with Lifetime Capability. This equipment will enhance research focused on biomolecules, biomimetic probes and compounds, and novel materials. Some specific projects include a) characterization of materials used for multiphoton optical memory; b) molecular sensors for DNA damage detection; c) DNA-fluorophore conjugates; d) development of efficient reactions for stereoselective organic synthesis; e) interactions of phospholipases with interfaces; and f) allosteric control of metabolic pathways. Investigators at several institutions in the Boston area will also use the spectrofluorometer. The fluorescence spectrometer counts photons of light in the ultraviolet (UV) and visible regions. When a sample of material is illuminated by UV light at a given frequency or energy, the reflected light consists of the original UV light, but also may contain light in the visible region of the spectrum, at a lower frequency or energy. The fluorometer is a very sensitive instrument used to detect the fluorescence signal.

通过化学研究工具和设施（CRIF）计划的奖项，波士顿学院的化学系将获得具有寿命能力的频谱荧光计。该设备将增强关注生物分子，仿生探针和化合物以及新型材料的研究。 一些特定的项目包括a）用于多光子光学内存的材料的表征； b）用于DNA损伤检测的分子传感器； c）DNA氟化合物偶联物； d）开发有效的有机合成反应； e）磷脂酶与界面的相互作用； f）代谢途径的变构控制。 波士顿地区几个机构的研究人员也将使用频谱荧光仪。 荧光光谱仪计数紫外线（UV）和可见区域中光的光子。当材料以给定频率或能量以紫外线照亮样品时，反射光由原始的紫外线组成，但也可能在频谱的可见区域中以较低的频率或能量包含光。荧光计是一种非常灵敏的仪器，用于检测荧光信号。