CAREER: Cyclophane Carbenes: Nucleophilicity and Catalytic Applications

职业：环芳卡宾：亲核性和催化应用

• 批准号: 0092434
• 负责人: Steven Diver
• 金额: $ 51万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0092434&HistoricalAwards=false
• 关键词: CAREER; Cyclophane; Carbenes; Nucleophilicity; Catalytic

The nucleophility of imidazole and benzimidazole carbenes will be explored. Novel achiral and chiral [2.2] imidazolophanes will be synthesized and their nucleophilic reactivity investigated. The educational component of the plan will introduce a form of collaborative learning into an honors organic chemistry lab course. Students will be divided into small groups and visit several stations (self-contained experiments) during their lab periods. Outreach to elementary schools in terms of demonstrations and hands-on activities is also part of the educational plan.With this CAREER award, the Organic Synthesis Program is supporting the research and educational activities of Professor Steven T. Diver of the Department of Chemistry at the State University of New York, Buffalo. The fundamental chemistry of a class of compounds known as imidazole carbenes will be studied. Encapsulation of these carbenes into a rigid framework which may confer unusual properties onto these molecules will also be accomplished. The educational portion of the plan will continue the PI's visits to elementary schools to give demonstrations and allow the implementation of the PI's cooperative learning modules into an honors organic chemistry lab course.

将探索咪唑和苯咪唑碳烯的核激活性。 新型的心理和手性[2.2]将合成咪唑酚，并研究其亲核反应性。 该计划的教育部分将将协作学习形式引入荣誉有机化学实验室课程。 学生将分为小组，并在实验室期间访问多个站（独立实验）。 在示威活动和实践活动方面向小学推广也是教育计划的一部分。有了本职业奖，有机综合计划正在支持纽约州立大学化学系的史蒂文·T·D·斯蒂夫·迪维（Steven T. Diver）教授的研究和教育活动。 将研究一类称为咪唑卡宾斯的化合物的基本化学。 将这些卡宾人封装成一个刚性框架中，该框架可能会赋予这些分子不寻常的特性。 该计划的教育部分将继续PI访问小学以进行示威，并允许PI合作学习模块实施荣誉有机化学实验室课程。