MRI: Development of High-Performance Scanning Cytometry Instrumentation for Tissue Engineering

MRI：开发用于组织工程的高性能扫描细胞仪

• 批准号: 9871365
• 负责人: Jeffrey Price
• 金额: $ 59.94万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-15 至 2001-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9871365&HistoricalAwards=false
• 关键词: MRI; Development; Performance; Scanning; Cytometry

9871365 Price The goal of this research is to develop a new high performance scanning cytometer for bioengineering research. Scanning flow cytometry involves imaging cells and cell response while under flow, shear or strain conditions. This research could significantly improve both the resolution and time constraints governing the current state-of-the-art. The specific aims include: (1) developing the cytometry hardware for high-resolution, high speed two dimensional scanning cytometry, (2) implementing cell classifier and software interfaces, (3) developing a multi-day time-lapse station for laser ablation or micromanipulator sorting, and (4) initiating the development of high speed three dimensional scanning cytometry. ***

9871365 价格 本研究的目标是开发一种用于生物工程研究的新型高性能扫描细胞仪。 扫描流式细胞术涉及在流动、剪切或应变条件下对细胞和细胞反应进行成像。 这项研究可以显着提高当前最先进技术的分辨率和时间限制。 具体目标包括：(1) 开发用于高分辨率、高速二维扫描细胞计数的细胞计数硬件，(2) 实现细胞分类器和软件接口，(3) 开发用于激光消融或细胞分析的多日延时站显微操作器分选，以及（4）启动高速三维扫描细胞术的开发。 ***