High-Field Multinuclear NMR In Undergraduate Education at Washington and Lee University

华盛顿与李大学本科教育中的高场多核核磁共振

基本信息

批准号：
9650033
负责人：
Erich Uffelman
金额：
$ 9.95万
依托单位：
Washington and Lee University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
1996
资助国家：
美国
起止时间：
1996-06-01 至 1998-05-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=9650033&HistoricalAwards=false
关键词：
Field Multinuclear NMR Undergraduate Education

项目摘要

This project supports development of a series of undergraduate experiments involving high-field nuclear magnetic resonance (NMR). These new experiments are being employed throughout the curriculum, ranging from general chemistry to undergraduate research. Many of the experiments are designed to make links between courses. For example, in collaboration with the Waymouth group at Stanford, a suite of experiments for undergraduates involving new oscillating Ziegler-Natta polymerization catalysts is being implemented. This experiment begins in organic chemistry with the synthesis of ligands and concludes in inorganic chemistry with the synthesis of the catalyst and the study of the polymerization process. Similarly, cross-disciplinary experiments are being developed involving porphyrin synthesis, spectroscopic characterization, and metallation. Routine use of 1H NMR becomes possible in the large organic class, and regular use of 13C NMR and two-dimensional NMR techniques is possible in the spectroscopy class. Pre-existing undergraduate research programs in synthesis, catalysis, and protein structure can flourish with the acquisition of the new high-field NMR, and new research initiatives in polymer chemistry are being made possible. The new experiments currently under development, as well as those being planned, can be disseminated in the educational literature as laboratory manuals and journal articles, as well as presented at conferences. Research results may generate both student and faculty presentations at conferences and scholarly papers in the chemical literature.

该项目支持开发一系列涉及高场核磁共振（NMR）的本科实验。这些新实验在整个课程中都采用，从一般化学到本科研究。许多实验旨在在课程之间建立联系。例如，与斯坦福大学的Waymouth Group合作，正在实施一套针对涉及新振荡Ziegler-Natta聚合催化剂的本科生的实验套件。该实验始于有机化学，从配体的合成开始，并结论是无机化学的，与催化剂的合成和聚合过程的研究。同样，正在开发跨学科实验，涉及卟啉合成，光谱表征和金属化。在大型有机类别中，通常使用1H NMR的常规使用，并且在光谱类别中可能定期使用13C NMR和二维NMR技术。合成，催化和蛋白质结构的本科生研究计划可以通过获得新的高场NMR而蓬勃发展，并且正在使聚合物化学方面的新研究计划成为可能。目前正在开发的新实验以及正在计划的实验可以在教育文献中以实验室手册和期刊文章以及会议介绍。研究结果可能会在化学文献中在会议和学术论文中产生学生和教师演讲。