Investigating the non-canonical roles of DEPDC5 in brain development and diseases by in vivo functional genomics

通过体内功能基因组学研究 DEPDC5 在大脑发育和疾病中的非典型作用

• 批准号: 468260
• 负责人: Samarut Eric
• 金额: $ 69.38万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2027-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468260&lang=en
• 关键词: Epilepsy; Functional Genomics; Genetics; Zebrafish

About 1% of the Canadian population is affected by epilepsy. Although many mutations in genes involved in neuronal excitability have been identified as causative, other mutations in non-classical epilepsy genes have also been found. This is the case of mu

加拿大人口的约1％受癫痫的影响。尽管已经确定为神经元兴奋性的基因中的许多突变已被鉴定为致病性，但也发现了非经典癫痫基因的其他突变。这就是MU的情况