Synthetic, Structural, and Mechanistic Studies of Organo- metallic Compounds Derived from Three-Membered Organic Rings

三元有机环衍生的有机金属化合物的合成、结构和机理研究

• 批准号: 9224467
• 负责人: Russell Hughes
• 金额: $ 26.4万
• 依托单位: Dartmouth College
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-05-15 至 1997-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9224467&HistoricalAwards=false
• 关键词: Synthetic; Structural; Mechanistic; Studies; Organo

With the support of this award in the Inorganic, Bioinorganic, and Organometallic Program, Dr. Russell P. Hughes of the Chemistry Department, Dartmouth College, would continue investigations on the cleavage and formation of carbon-carbon bonds promoted by transition metals. Three projects would be pursued: ring-opening in vinylcyclopropene rearrangements; characterization of eta-3-cyclopropenyl complexes, including their CO substitution reactions and rotation barriers; and bond cleavage of sterically destabilized cyclopentadienyl ligands. The latter reactions do not proceed by simple metal insertion into the carbon-carbon bond. In order to study the skeletal rearrangments that occur during the ring opening reactions of the cyclopentadienyl ligands, selectively isotopically labelled precursors will be prepared. A 1,2,3,-tri-t-butylcyclopenta- dienyl ligand has been prepared; advantage will be made of the incipient strain associated with the compound in order to make novel compounds. %%% By investigating in detail the mechanism of carbon-carbon bond making and breaking by transition metals, Dr. Russell P. Hughes of Dartmouth College hopes to achieve increased understanding of this reaction which is important to the petroleum catalyst industry. The results could be particularly relevant to the formation and control of carbon ring compounds.

在无机，生物有机和有机金属计划中的该奖项的支持下，达特茅斯学院化学系的Russell P. Hughes博士将继续对通过过渡金属促进的碳碳债券的裂解和形成。 将追求三个项目：乙烯基环丙烯重排的戒指； ETA-3-环丙基烯基复合物的表征，包括它们的CO取代反应和旋转障碍；和粘结性的粘结不稳定的环戊二烯基配体。 后一种反应不会通过简单的金属插入碳碳键来进行。 为了研究环戊二烯基配体的环开反应期间发生的骨骼重排，将制备有选择的同位素标记的前体。 已经制备了1,2,3，-tri-t叔丁基环体 - 二烯基配体；与化合物相关的初期菌株将有优势，以制成新颖的化合物。 达特茅斯学院的Russell P. Hughes博士详细研究碳碳结合和破坏的机制，希望对这一反应提高理解，这对石油催化剂行业很重要。 结果可能与碳环化合物的形成和控制特别相关。