Gel Permeation Chromatograph

凝胶渗透色谱仪

• 批准号: 9212115
• 负责人: Alan Russell
• 金额: $ 5.84万
• 依托单位: University of Pittsburgh
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-01 至 1994-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9212115&HistoricalAwards=false
• 关键词: Gel; Permeation; Chromatograph

This equipment is to be used for investigations of the (bio)catalytic synthesis of polymers in supercritical fluids. Specifically, the identification of enzymes for the synthesis of poly(ethylene terephthalate), poly(ethylene glutamate), and peptide synthesis is to be carried out. In addition, the use of supercritical fluids as solvents for traditional polymerization is to done. Previous work on the (bio)catalytic transesterification of acrylates has produced a set of general guidelines for the optimization of enzymatic processes in supercritical environments. Using these guidelines, this project is to establish the feasibility of the (bio)catalytic synthesis of aromatic and aliphatic polyesters.

该设备用于研究超临界流体中聚合物的（生物）催化合成。 具体而言，将进行聚对苯二甲酸乙二醇酯、聚谷氨酸乙二醇酯的合成和肽合成的酶的鉴定。 此外，使用超临界流体作为传统聚合的溶剂也已完成。 先前关于丙烯酸酯的（生物）催化酯交换反应的工作已经为超临界环境中酶促过程的优化制定了一套通用指南。利用这些指南，该项目旨在建立芳香族和脂肪族聚酯（生物）催化合成的可行性。