A Workshop on Vitamin K Dependent Proteins

维生素 K 依赖性蛋白质研讨会

• 批准号: 8912374
• 负责人: C. Fred Fox
• 金额: $ 0.85万
• 依托单位: University of California-Los Angeles
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-04-15 至 1989-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8912374&HistoricalAwards=false
• 关键词: Workshop; Vitamin; Dependent; Proteins

It is important to continue searching for new approaches that will allow the economic recovery of proteins via plasma fractionation. The proposed workshop will bring together experts from industry and academia to probe the many questions concerning protein recovery and attempt to lay out a workable strategy for protein recovery that will consider the many pitfalls in this competitive industry. Many people are suffering and dying from hereditary diseases caused by protein deficiencies or imbalances. There are more than one dozen known plasma proteins that might be recovered with the application and refinement of existing and/or developing separation and purification techniques. Most of these proteins are high molecular weight (50,000) and therefore, it is purely speculative as to when or if ever they will be manufactured by rDNA techniques or chemical synthesis.

重要的是继续寻找新的方法，通过血浆分离经济地回收蛋白质。 拟议的研讨会将汇集来自工业界和学术界的专家，探讨有关蛋白质回收的许多问题，并尝试制定可行的蛋白质回收策略，以考虑这个竞争激烈的行业中的许多陷阱。 许多人因蛋白质缺乏或失衡引起的遗传性疾病而遭受痛苦和死亡。 有十多种已知的血浆蛋白可以通过应用和改进现有和/或正在开发的分离和纯化技术来回收。 大多数这些蛋白质都是高分子量的（50,000），因此，它们何时或是否会通过 rDNA 技术或化学合成制造纯粹是推测。